: Dr. Surender Kumar Yachha
2. Present Designation : Professor and Head
3. Email and Office address: Department of Pediatric Gastroenterology
Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India. Telephone: PABX numbers: 2668700/800/900 Ext: 2432 (Off), 2932 (Residence) Fax: 00-91-522- 2668017 and 2668078.
4. Brief para about education,training and awards: Education and training MBBS - University of Kashmir MD (Pediatrics) - Postgraduate Institute of Medical Education and Research, DM (Gastroenterology) -(PGIMER) Chandigarh Commonwealth medical fellowship in Pediatric Hepatologyand Pediatric liver transplantation (medical aspects) - King’s College, School of Medicine and Awards/Scholarships/Medals
i. Best paper award: Positive impact of awareness campaign on referral of
neonatal cholestasis syndrome in India. Abhinav Sharma, U Poddar and SK Yachha. 14th Biennial Conference of Asian Pacific Association for the Study of the Liver, December 2004, New-Delhi. J Gastroenterol. Hepatol. 2004;19 (Suppl.):A800
ii. Best paper award: Does co-infection with multiple viruses adversely
influence the course and outcome of sporadic acute viral hepatitis in children? Yachha SK, kumar A, Poddar U, Bharadia L, Aggarwal R. XIIIth Annual conference of Pediatric Gastroenterology, September, 2003 (Pune).
iii. Olympus Mitra Endoscopy Award by Indian Society of Gastroenterology,
iv. Fellow of Indian Academy of Pediatrics (FIAP) for outstanding contribution
v. Best paper award on paper entitled “ Autoimmune liver disease in children:
is it worth a search? Chetri K, Srivastava A, Yachha SK, Saraswat VA, Pandey R”. Annual Conference of Indian Association for the study of the liver. November 1999, Calcutta.
vi. Best paper award on paper entitled "Association of HLA-DR and DQ
antigens in celiac disease a family study". Agarwal S, Gupta A, Muller-Myhsok B, Mehrotra P, Yachha SK, Agarwal SS. 6th Annual Conference of
IAP Chapter of Pediatric Gastroenterology and Commonwealth Association of Pediatric Gastroenterology and Nutrition Update. November 1998, New Delhi.
vii. Commonwealth Medical Fellowship in Pediatric Hepatology and Liver Transplantation, Kings College Hospital, school of Medical and Dentistry London (UK) 1995-96.
viii. Manchanda Gold Medal, Indian Academy of Pediatrics, December 1986 for
ix. National Merit Scholarship, 1971 - 1978.
5. Specialization and Research interest: Pediatric Gastroenterology and Hepatology;
Portal hypertension, celiac disease, Neonatal
6. List of selected publications:
1. Yachha SK, Patwari AK, Bhan S, Hussain A, Singh D. Cerebrospinal fluid & blood
glucose levels in febrile convulsions. Indian Pediatrics 1981, 18, 117-119.
2. Yachha SK, Marwaha RK, Narang A, Mohanty D. Glucose-6-Phosphate dehydrogenase
isoenzyme pattern and evaluation of screening methods for G-6-PD deficiency in neonatal hyperbilirubinemia. Indian Pediatrics, 1987, 24: 1099-1103.
3. Thapa BR, Yachha SK, Mehta S. Crigler-Najjar Syndrome type II with Kernicterus. Indian
4. Kumar A, Marwaha RK, Yachha SK, Saroda R, Grewal G. Infantile Gaucher's disease.
5. Thapa BR, Yachha SK, Narsimharao KL, Gupta HL, Kataryia S, Mehta S. Multinodular
infantile hemangioendothelioma of liver. Indian Pediatrics 1988, 25: 199-203.
6. Yachha SK, Kochhar R, Mehta S. Endoscopic dilatation of esophageal strictures. Indian
7. Bhasin D, Yachha SK, Ayyagiri A, Singh V, Kochhar R, Malik A, Mehta S. How specific is
the rapid urease test for diagnosing compylobacter pylori? Journal of Clinical Pathology 1989, 46: 671.
8. Marwaha N, Sarode R, Marwaha RK, Sharma S, Yachha SK, Narang A. Bilirubin Crystals
in peripheral blood smears from neonates with unconjugated hyperbilirubinaemia. Medical Laboratory Sciences 1990, 47, 278-281.
9. Thapa BR, Yachha SK, Mehta S. Abdominal tuberculosis. Indian Pediatrics 1991, 28:
10. Mishra S, Hiranandani M, Yachha SK, Malik Ak, Mehta S, Thapa BR. Niemann-pick
disease presenting as hepatic disorder. Indian J of Gastroenterology. 1992; 11: 39-40.
11. Mishra S, Thapa BR, Yachha SK, Malik AK, Mehta S. Hepatic manifestations in sickle
cell disease in childhood. Indian Pediatrics 1992; 29: 501-504.
12. Singh V, Yachha SK, Thapa BR, Mehta S. Antibodies to hepatitis C Virus (anti-HCV) in
Children. Indian Pediatrics 1991; 28: 1532-33.
13. Kumar P, Yachha SK, Misra S, Mehta S. Histamine-2 receptor antagonists. Indian
14. Misra S, Kumar P, Mehta S, Yachha SK, Malik AK, Negi B, Rao KL Narasimha.
Tubercular stricture of the duodenum in a child. J Paediatr Child Health, 1992; 28: 338.
15. Yachha SK, Misra S, Malik AK, Nagi B, Mehta S. Spectrum of malabsorption syndrome In
North Indian children. Indian J of Gastroenterology 1993; 12:120-125.
16. Das A and Yachha SK. Unusual presentation of tuberculous peritonitis. Indian Pediatrics
17. Yachha SK and Ghoshal UC. Luminal gastrointestinal disease and the Indian J
18. Yachha SK and Ghoshal UC, Hepatits C Virus (HCV) Infection in pediatric practice
(Editorial). Indian Pediatrics, 1993; 30:739-744.
19. Kumar M, Puri AS, Yachha SK. Pseudomembranous Colitis. Indian Pediatrics, 1993;
20. Yachha SK, Singh V, Kanwar SS, Mehta S. Epidemiology subgroups and serotypes of
rotavirus diarrhea in North Indian communities. Indian Pediatrics 1994; 31:27-33.
21. Kumar M, Puri AS, Srivastava R, Yachha SK. Solitary rectal ulcer in a child treated with
local sulfasalazine. Indian Pediatrics, 1994; 31: 1553-1555.
22. Aggarwal P, Phadkhe RV, Baijal SS, Yachha SK, Sharma BC, Poddar U. Calcific
pancreatitis induced gastroduodenal artery pseudoaneurysm syndrome: non-surgical management. Pediatric Radiology, 1994; 24: 539-540.
23. Yachha SK, Sharma BC. Childhood hepatitis. Indian J of Pediatrics 1994; 61: 665-673. 24. Poddar U, Ghoshal UC, Yachha SK. Spontaneous bacterial peritonitis. Acta Oncologica
25. Sharma BC, Yachha SK, Kulshreshta A, Ghoshal UC, Kumar A. Duodenocolic fistula in a
child. Pediatric Surgery International 1995; 10: 396-397.
26. Ghoshal UC, Saraswat VK, Yachha SK. Association of splenic vein obstruction and
coeliac disease in an Indian patient. J of Hepatology 1995; 23: 358.
27. Goenka MK, Mehta S, Yachha SK, Nagi B, Malik AK, Chakraborty A. Hepatic involvement
combinating with cirrhosis in a child with disseminated cryptococcosis. J Clin Gastroenterol 1995; 20: 57-60.
28. Yachha SK, Ghoshal UC, Gupta R, Sharma BC, Ayyagari A. Portal hypertensive
gastropathy in children with extrahepatic portal venous obstruction: role of variceal obliteration by endoscopic sclerotherapy and Helicobacter pylori infection. J Pediatr Gastroenterol and Nutrition 1996; 23: 20-23.
29. Kumar M, Yachha SK, Gupta RK. Neonatal cholestasis due to galactosemia Indian J
30. Kumar M, Yachha SK, Aggarwal R, Prasad KN, Ayyagari A, Naik SR. Healing of chronic
antral gastritis: cytoprotection vs antibacterial treatment. Indian J Gastroenterol 1996; 15: 90-93.
31. Yachha SK, Khanduri A, Sharma BC, Kumar M. Gastrointestinal bleeding in children. J
Gastroenterol and Hepatology 1996, 11: 903-907.
32. Yachha SK, Khanduri A, Kumar M, Saxena R, Sikora SS, Gupta RK. Neonatal cholestasis
syndrome-an appriasal at a tertiary centre. Indian Pediatrics 1996; 33: 729-734.
33. Kumar M, Yachha SK, Khanduri A, Prassad KN, Ayyagari A, Pandey R. Endoscopic,
histologic and microbiologic evaluation of children with upper abdominal pain. Indian Pediatrics 1996; 33: 905-909.
34. Yachha SK, Srivastava A, Sharma BC, Khanduri A, Baijal SS. Therapeutic gastrointestinal
endoscopy. Indian J Pediatrics 1996; 63: 633-639.
35. Kumar M, Puri AS, Yachha SK, Saxena R, Baijal SS, Pandey R. Benign non-traumatic
stricture of common hepatic duct in a child. J Pediatr Gastroenterol and Nutrition 1996; 22: 395-397.
36. Sharma BC, Yachha SK, Mishra RN, Gupta D. Hypoplastic anemia associated with
ulcerative colitis in a child. J Pediatr Gastroenterol and Nutrition 1996; 23: 326-328.
37. Yachha SK, Dhiman RK, Gupta R, Ghoshal UC. Endosonographic evaluation of rectum
in children with extrahepatic portal venous obstruction. J Pediatr Gastroenterol and Nutrition 1996; 23: 438-441.
38. Yachha SK, Sharma BC, Kumar M, Khanduri A. Endoscopic sclerotherapy for
esophageal varices in children with extrahepatic portal venous obstruction: a follow up study. J Pediatr Gastroenterol and Nutrition 1997; 24: 49-52.
39. Ravi Shanker B, Yachha SK, Sharma BC, Singh B, Mahant TS, Kapoor VK. Retained
esohageal foreign bodies in children. Pediatric Surgery International 1996; 11: 544-546.
40. Yachha SK, Sharma BC. Current status of hepatobiliary disorders in children. Indian
41. Mehrotra RN, Bhatia V, Dabadghao P, Yachha SK. Extrahepatic portal vein obstruction in
children: Anthropometry, Growth hormone and Insulin-like growth factor 1. J Pediatr Gastroenterol and Nutrition 1997; 25: 520-523.
42. Aggarwal R, Shahi H, Naik S, Yachha SK, Naik SR. Evidence in favour of high infection
rate with hepatitis E virus among young children in India. J Hepatology 1997; 26: 1425-6.
43. Yachha SK, Srivastava A. Images in clinical practice. Indian Pediatrics 1998; 35: 67-69. 44. Yachha SK, Srivastava A. Images in clinical practice. Indian Pediatrics 1998; 35: 175-
45. Mehrotra P and Yachha SK. Need for liver transplantation in Indian children. Indian
46. R Aggarwal, S Naik, Yachha SK, SR Naik. Seroprevalence of antibodies to hepatitis A
virus among children in Northern India. Indian Pediatrics 1999; 36: 1248-50.
47. Yachha SK and Mohindra S. Neonatal cholestasis syndrome. Indian J of Pediatrics 1999;
48. Aggarwal S, Gupta A, Yachha SK, Myhsok, MB Mehrotra P, Aggarwal SS. Association of
HLA-DR and DQ antigens in coeliac disease: a family study. J Gastroenterol and Hepatology 2000; 15: 771-774.
49. Consensus Report on Neonatal Cholestasis Syndrome (NCS). Pediatric Gastroenterology
subspecialty chapter of Indian Academy of Pediatrics document. (SK Yachha, as coordinator). Indian Pediatrics. Indian Pediatrics 2000; 37:845-851.
50. Dadhich SK, Yachha SK, Sikora SS, Srivastava A, Pandey R. Endoscopic and histologic
evaluation of reflux esophagitis in children. Indian Pediatrics 2000; 37:1111-1114.
51. Yachha SK Management of chronic hepatitis B virus infection in children. Indian J
52. Yachha SK, Aggarwal R, Sharma BC, Misra RN, Aggarwal A, Naik SR. Functional protein
C and anti- cardiolipin antibody in children with portal vein thrombosis. Indian J Gastroenterol 2001; 20: 47-49.
53. Yachha SK. Non- viral infections of liver. International Seminars in Pediatric
Gastroenterology and Nutrition 2001; 10(1): 5-7
54. Yachha SK, Srivastava A, Chetri K, Saraswat VA, Krishnani N. Autoimmune liver disease
in children. J Gastroenterol and Hepatol 2001; 16: 674-677.
55. Mohindra S, Yachha SK, Srivastava A, Krishnani N, Agarwal R, Ghoshal UC, Prasad KK,
Naik SR. Celiac disease in Indian children: Assessment of clinical, nutritional and pathologic characteristics. Journal of Health, Population and Nutrition 2001; 19: 204-208.
56. Yachha SK, Chetri K and Lal R. Management of Portal Hypertension. Indian J Pediatrics
57. Yachha SK. Portal hypertension in children: An Indian perspective. J Gastroenterol and
58. Peter L, Dadhich SK, Yachha SK. Clinical and laboratory differentiation of cirrhosis
and extrahepatic portal venous obstruction in children J Gastroenterol Hepatol 2003 Feb; 18(2): 185-189
59. Yachha SK, Chetri K, Saraswat VA, Baijal SS, Sikora SS, Lal R, Srivastava A.
Management of childhood pancreatic disorders: a multidisciplinary approach. J Pediatr Gastroenterol Nutr. 2003 Feb; 36(2): 206-12.
60. Singh M, Prasad KN, Yachha SK, Krishnani N. Genotypes of Helicobacter pylori in
children with upper abdominal pain. J Gastroenterol Hepatol. 2003 Sep;18 (9):1018-23
61. Singh H K, Yachha S K, Saxena R, Gupta A, Nagana Gowda GA, Bhandari M, Khetrapal
CL. A new dimension of 1H-NMR spectroscopy in assessment of liver graft dysfunction. NMR in Biomed. 2003 Jun; 16(4): 185-8
62. Wagholikar GD, Chetri K, Yachha SK, Sikora SS. Spontaneous perforation- rare
complication of choledochal cyst. Indian J Gastroenterol. 2004 May-June;23(3):111-2
63. Yachha SK(Editorial) Cholestatic jaundice during infancy. Indian J Gastroenterol. 2005
64. Yachha SK, Sharma A. Neonatal cholestasis in India. Indian Pediatr. 2005 May;43:491-2 65. Poddar U and Yachha SK. Pancreatic diseases in children. Indian Pediatrics 2005;
66. Singh M, Prasad KN, Yachha SK, Saxena A, Krishnani N. Helicobacter pylori infection in
children: prevalence, diagnosis and treatment outcome. Trans R Soc. 2006; 100: 227-233.
67. Srivenu Itha and Yachha SK. Endoscopic outcome beyond esophageal variceal
obliteration in children with extrahepatic portal venous obstruction. J Pediatr Gastroenterol Nutr. 2006;February 42(2):196-200
68. Singh M, Prasad KN, , Saxena A, Yachha SK. Helicobacter pylori induces apoptosis of T-
and B cell lines and translocates mitochondrial apoptosis– inducing factor to nucleus. Current Microbiology 2006;xx:1-8
69. Singh M, Prasad KN, Krishnani N, Saxena A, Yachha SK. Helicobacter pylori infection,
histopathological gastritis and gastric epithelial cell apoptosis in children. Acta Paediatrica 2006;95:732-737
70. Yachha SK, Aggarwal R , Srinivas S, Srivastava A, Somani SK, Srivenu Itha. Antibody
Testing in Indian children with celiac Disease. Indian J Gastroenterol. 2006;25: 132-135
71. Yachha SK and Poddar U. Reader’s Forum “Acute viral hepatitis” Indian Pediatrics.
72. Yachha SK. Celiac disease- India on the Global Map (Editorial). J Gastroenterol
73. Kumar A, Yachha SK, Poddar U, Singh U, Aggarwal R. Does co-infection with multiple
viruses adversely influence the course and outcome of sporadic acute viral hepatitis in children? J Gastroenterol Hepatol. 2006; 21:1533-7.
74. Yachha SK and Khanna V. Ascites in childhood liver disorders. Indian J Pediatrics.2006;
75. Vijayaraghavan P, Lal R, Sikora SS, Poddar U, Yachha SK. Experience with
choledochal cysts in infants. Pediatr Surg Int. 2006; 22(10):803-7.
76. Sharma S, Kumar SI, Poddar U, Yachha SK, Aggarwal R. Factor V leiden and
prothrombin gene G20210 A mutations are uncommon in portal vein thrombosis in India. Indian J Gastroenterol. 2006; 25: 236-239.
77. Yachha SK, Srivastava A, Mohindra S, Krishnani N, Aggarwal R, Saxena A. Effect
of Gluten-Free Diet on Growth and Small Bowel Histology in children with Celiac Disease in India. J Gastroenterol Hepatol. (In press).
RELAZIONE DELLA COMMISSIONE Relazione sulla politica di concorrenza 2012 INTRODUZIONE L’Unione europea (UE) è il più grande spazio economico e commerciale al mondo. Il suo mercato unico, che comprende oltre mezzo miliardo di consumatori e più di 20 milioni di imprese, costituisce una risorsa unica e un incomparabile vantaggio competitivo sulla sce
Correspondence Early bactericidal Diacon AH, Dawson R, von Groote-Bidlingmaier F, et al. 14 day isolation, are of little use to patients bactericidal activity of PA-824, bedaquiline, activity of new drug pyrazinamide, and moxifl oxacin combinations: a randomised trial. Lancet 2012; 380: 986–93. regimens for of the disease. Drug combinations 2 Udwadia ZF. MDR, XDR, TDR