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1.1. Bachmann S, Goldschmid A: Fine structure of the axial complex of Sphaerechinus granularis (Echinodermata:Echinoidea). Cell Tiss Res 193: 107-123, 1978 1.2. Bachmann S, Goldschmid A: Ultrastructural,fluorescence microscopic and microfluorimetric study of the innervation of the axial complex in the sea urchin, Sphaerechinus granularis. Cell Tiss Res 194: 315-326, 1978 1.3. Bachmann, S: Die Feinstruktur des Axialkomplexes beim Seeigel (Sphaerechinus granularis) Dissertation,
1.4. Bachmann S, Pohla H, Goldschmid A: Phagocytes in the axial complex of the sea urchin, Sphaerechinus
granularis. Cell Tiss Res 213: 109-120, 1980 1.5. Bachmann S, Kriz W: Histotopography and ultrastructure of the thin limbs of the loop of Henle in the hamster. 1.6. Bachmann S, Kriz W, Kuhn C, Franke WW: Differentiation of cell types in the mammalian kidney by immunofluorescence using antibodies to intermediate filament proteins and desmoplakins. Histochemistry 77: 365-394, 1983 1.7. Mickisch O, Bommer J, Bachmann S, Waldherr R, Mann JE, Ritz E: Multicystic transformations of kidneys in chronic renal failure. Nephron 38: 93-99, 1984 1.8. Minuth WW, Lauer G, Bachmann S, Kriz: Immunocytochemical localization of a renal glycoprotein (gpCD1) synthesized by cultured collecting duct cells. Histochemistry 80: 171-182, 1984 1.9. Koeppen-Hagemann I, Bachmann S, Minuth WW, Kriz W: Immunohistochemical localization of a protein fraction derived from rabbit renal papilla. Histochemistry 81: 457-464, 1984 1.10. Kaissling B, Bachmann S, Kriz W: Structural adaptation of the distal convoluted tubule to prolonged furosemide treatment. Am J Physiol 248: F374-F381, 1985 1.11. Bachmann S, Koeppen-Hagemann I, Kriz W: Ultrastructural localization of Tamm-Horsfall glycoprotein (THP) in rat kidney as revealed by protein A-gold immunocytochemistry. Histochemistry 83: 531-538, 1985 1.12. Kriz W, Bachmann S: Pre- and postglomerular arterioles of the kidney. J Cardiovasc Pharmacol 7: S24-S30, 1.13. Bachmann S, Gilbert P, Minuth WW: Electron microscopic immunogold localization of a collecting duct antigen (PCD2) in intercalated and principal cells of rabbit kidney. Cell Tiss Res 249: 633-640, 1987 1.14. Gilbert P, Minuth WW, Bachmann S: Microheterogeneity of the collecting duct system in rabbit kidney as revealed by monoclonal antibodies. Cell Tiss Res 248: 611-618, 1987 1.15. Bouby N, Bachmann S, Bankir L: Effect of water intake on the progression of chronic renal failure in the 5/6 nephrectomized rat. Am J Physiol 258: F973-F979, 1990 1.16. Bachmann S: Tamm-Horsfall Protein bei der Ratte. Immunzytochemische Lokalisation und Ausscheidung unter verschiedenen Bedingungen. Habilitationsschrift, Heidelberg, 1990 1.17. Bachmann S, Metzger R, Bunnemann B: Tamm-Horsfall protein-mRNA synthesis is localized to the thick ascending limb of Henle's loop in rat kidney. Histochemistry 94: 517-523, 1990 1.18. Bachmann S, Dawnay A, Bouby N, Bankir, L: Tamm Horsfall-Protein excretion during chronic alterations in urinary concentration and protein intake in rat. Renal Physiol and Biochem 14: 236-245, 1991 1.19. Lee M, Zhao Y, Peters J, Ganten D, Zimmermann F, Ganten U, Bachmann S, Bader M, Mullins JJ: The preparation of transgenic rats expressing the mouse Ren-2 Gene. J Vasc Med Biol 3(1): 50-54, 1991 1.20. Bachmann S, Peters J, Engler E, Ganten D, Mullins J: Transgenic rats carrying the mouse renin gene - morphological characterization of a low renin hypertension model. Kidney Int. 41: 24-36, 1992 1.21. Schneble F, Bonzel K, Waldherr R, Bachmann S, Roth H, Schärer K: Peritoneal morphology in children treated by continous ambulatory peritoneal dialysis. Pediatr Nephrol 6: 542-546, 1992 1.22. Ganten D, Wagner J, Zeh K, Köller M, Bader M, Michel JB, Paul M, Zimmermann F, Ruf P, Hilgenfeld U, Ganten U, Kaling M, Bachmann, S, Mullins JJ, Murakami K: Species specificity of renin kinetics in transgenic rats harbouring the human and angiotensinogen genes. Proc Natl Acad Sci USA 89: 7806-7810, 1992 1.23. Mundel P, Bachmann S, Bader M, Fischer A, Kummer W, Mayer B, Kriz W: Expression of nitric oxide synthase in kidney macula densa cells. Kidney Int 42: 1017-1019, 1992 1.24. Bachmann S, Le Hir M, Eckardt K-U: Colocalization of erythropoietin mRNA and ecto-5'-nucleotidase immunoreactivity in peritubular cells of rat renal cortex indicates that fibroblasts produce erythropoietin. J Histochem Cytochem 41: 335-341, 1993 1.25. Kummer W, Bachmann S, Neuhuber W, Hänze J, Lang R: Tyrosine-hydroxylase-containing vagal afferent neurons in the rat nodose ganglion are independent from neuropeptide-Y-containing populations and project to esophagus and stomach. Cell Tissue Res 271: 135-144, 1993 1.26. Schröter J, Timmermans G, Seyberth HJ, Greven J, Bachmann S: Marked reduction of Tamm-Horsfall protein expression and urinary excretion in hyperprostaglandin E-syndrome. Kidney Int 44: 401-410, 1993 1.27. Heym C, Common B, Klimaschewski L, Couraud J-Y, Bachmann S: Neurochemistry, connectivity and plasticity of small intensely fluorescent (SIF) cells in rat superior cervical ganglion. Ann Anat 175: 309-319, 1993 1.28. Bachmann S, Mundel P: Nitric oxide in the kidney - Biochemistry, function and localization. Am J Kidney 1.29. Schäfer K, Gretz N, Bader M, Oberbäumer I, Bachmann S: Focal overexpression of collagen IV characterizes the initiation of epithelial changes in polycystic kidney disease. Exp. Nephrol 2: 190-195, 1994 1.30. Zhang YM, Bachmann S, Hemmer C, van Lunzen J, von Stemm A, Kern P, Dietrich M, Ziegler R, Waldherr R, Nawroth PP: Vascular origin of Kaposi's sarcoma. Expression of leukocyte adhesion molecule-1, thrombomodulin, and tissue factor. Am J Pathol 144: 51-59,1994 1.31. Schäfer K, Bader M, Gretz N, Bader M, Oberbäumer I, Eckardt KU, Kriz W, Bachmann S: Characterization of the Han:SPRD rat model for hereditary polycystic kidney disease. Kidney Int 46: 134-152, 1994 1.32. Bachmann S, Ramasubbu K, Schäfer K, Uiker S, Gretz N: Tubulo-interstitial changes in the Han:SPRD rat model for autosomal dominant polycystic kidney disease. Contrib Nephrol :113-117, 1995 1.33. Mundel P, Gambaryan S, Bachmann S, Koesling D, Kriz W: Immunolocalization of soluble guanylyl cyclase subunits in rat kidney. Histochemistry 103: 75-79, 1995 1.34. Bachmann S, Bosse HM, Mundel P: Topography of NO synthesis by localizing constitutive NO synthases in mammalian kidney. Am J Physiol 268: F885-F898, 1995 1.35. Falkenhahn M, Franke F, Bohle RM, Stauss HM, Zhu Y-C, Bachmann S, Danilov S, Unger T: Cellular distribution of angiotensin-converting enzyme after myocardial infarction. Hypertension 25: 219-226, 1995 1.36. Fischer E, Schnermann J, Briggs JP, Kriz W, Ronco P, Bachmann S: Distribution of NO synthase and compounds of the renin angiotensin system in the juxtaglomerular apparatus of the developing kidney. Am J. Physiol 268: F 1164-1176, 1995 1.37. Rasch R, Torffvit O, Bachmann S, Jensen PK, Jacobsen NO: Tamm Horsfall glycoprotein in Streptozotocin diabetic rats: a study of in situ hybridization, immunohistochemistry and urinary excretion. Diabetologia 38: 525-535, 1995 1.38. Bosse HM, Böhm R, Resch S, Bachmann S: Parallel regulation of constitutive NO synthase and renin at the juxtaglomerular apparatus of rat kidney under various stimuli. Am J Physiol 269: F793-F805, 1995 1.39. Obermüller N, Moser D, Kunchaparty S, Bernstein PL, Velázquez H, Ellison DH, Bachmann S: Expression of the thiazide sensitive Na/Cl cotransporter in rat and human kidney. Am J Physiol 269: F900-F910, 1995 1.40. Sharpe RM, Maguire SM, Saunders PTK, Millar MR, Russell LD, Ganten D, Bachmann S, Mullins L, Mullins JJ: Infertility in a transgenic rat due to impairment of cytoplasmic elimination and sperm release from the Sertoli cells. Biol. Reproduction 53: 214-226, 1995 1.41. Lee MA, Böhm M, Kim S, Bachmann S, Bachmann J, Bader M, Ganten D: Differential gene expression of renin and angiotensinogen in the TGR (mREN-2)27 transgenic rat. Hypertension 25: 570-580, 1995 1.42. Bachmann S, Velázquez H, Obermüller N, Moser D, Bernstein P, Ellison DH: Molecular localization of Na and Ca transport pathways along the rabbit kidney distal tubule. J Clin Invest 96: 2510-2514, 1995 1.43. Obermüller N, Kunchaparty S, Ellison DH, Bachmann S: Expression of the Na-K-2CI-cotransporter by macula densa and thick ascending limb cells of rat and rabbit nephron. Rapid . publication, J Clin Invest 98: 635-640, 1996 1.44. Klimaschewski L, Obermüller N, Majewski M, Bachmann S, Heym C: Increased expression of nitric oxide synthase in a subpopulation of rat sympathetic neurons after axotomy - correlation with vasoactive intestinal peptide. Cell Tissue Res 285: 419-425, 1996 1.45. Peters J, Kränzlin B, Schaeffer S, Zimmer J, Resch S, Bachmann S, Gretz N, Hackenthal E: Presence of renin within intramitochondrial dense bodies of the rat adrenal cortex. Am J Physiol 271: E439-E450, 1996 1. 46. Schmid C, Della Bruna R, Schricker K, Bachmann S, Kurtz A: Zonal expression of Angiotensin II-AT-| - receptor genes in rat kidneys. Exp Nephrol 4: 322-329, 1996 1.47. Gretz N, Kränzlin B, Pey R, Schieren G, Bach J, Obermüller N, Ceccherini I, Klöting I, Rohmeiss P, Bachmann S, Hafner M: Rat models of autosomal dominant polycystic kidney disease. Nephrol Dial Transplant 11, Suppl 6: 46-51, 1996 1.48. Bachmann S, Ramasubbu K: Immunohistochemical colocalization of the α-subunit of neutrophil NADPH oxidase and ecto-5'-nucleotidase in kidney and liver. Kidney Int 51: 479-482, 1997 1.49. Bosse HM, Bachmann S: Immunohistochemically detected protein nitration indicates sites of renal nitric oxide release in Goldblatt hypertension. Hypertension 30: 948-952, 1997 1.50. Vogel M, Luck G, Bachmann S, Blottner D: NOS type-mRNA expression and protein localization in spinal autonomic neurons. NeuroReport 8(15): 3389-3393, 1997 1.51. Ramasubbu K, Gretz N, Bachmann S: Increased epithelial cell proliferation and abnormal extracellular matrix in rat polycystic kidney disease. J Am Soc Nephrol 9: 937-945, 1998 1.52. Bachmann S, Oberbäumer I: Structural and molecular dissection of the juxtaglomerular apparatus: New aspects for the role of nitric oxide. Kidney Int 54 (Suppl. 67): S29-S33, 1998 1.53. Bostanjoglo M, Reeves B, Reilly R, Velázquez H, Robertson N, Litwack G, Morsing P, D∅rup J, Bachmann S, Ellison DH: 11β-hydroxysteroid dehydrogenase, mineralocorticoid receptor and thiazide-sensitive Na-CI cotransporter expression by distal tubules. J Am Soc Nephrol 9(8): 1347-1358, 1998 1.54. Oberbäumer I, Moser D, Bachmann S: Nitric oxide synthase 1 mRNA: Tissue-specific variants from rat with alternative first exons. Biol Chem 379: 913-919, 1998 1.55. Bachmann, Sebastian: Cell localization and ontogeny of sodium transport pathways in the distal nephron: perspectives in function and failure. Curr Opin Nephrol Hypertens 8: 31-38, 1999 1.56. Bennai F, Morsing P, Paliege A, Ketteler M, Mayer B, Tapp R, Bachmann S: Normalizing the expression of Nitric oxide synthase by low-dose AT1-receptor antagonism parallels improved vascular morphology in hypertensive rats. J Am Soc Nephrol 10: S104-S115, 1999 1.57. Schmitt R, Ellison DH, Farman N, Rossier BC, Reilly RF, Reeves WB, Oberbäumer I, Tapp R, Bachmann S: Developmental expression of sodium entry pathways in rat nephron. Am J Physiol 276: F367-F381, 1999 1.58. Shugrue CA, Obermüller N, Bachmann S, Slayman CW, Reilly RF: Molecular cloning of NHE3 from LLC- PK1 cells and localization in pig kidney. J. Am Soc Nephrol 10:1649-1657, 1999 1.59. Thomson SC, Bachmann S, Bostanjoglo M, Ecelbarger CA, Peterson OW, Schwartz D, Bao D, Blantz RC: Temporal adjustment of the juxtaglomerular apparatus during sustained inhibition of proximal reabsorption. J Clin Invest 104(8): 1149-1158, 1999 1.60. Bachmann S, Bostanjoglo M, Schmitt R, Ellison DH: Sodium transport-related proteins in the mammalian distal nephron - distribution, ontogeny and functional aspects. Anat Embryol 200: 447-468, 1999 1.61. Bachmann S, Theilig F: Appareil juxtaglomérulaire, monxyde d'azote et signalisation à la macula densa. Actualités néphrologiques Jean Hamburger Hôpital Necker 2000, 245-254, 2000 1.62. Persson AEG, Bachmann S: Constitutive nitric oxide synthesis in the kidney - functions at the juxtaglomerular apparatus. Acta Physiol Scand 169: 317-324, 2000 1.63. Vogel M, Kränzlin B, Biber J, Murer H, Gretz N, Bachmann S:Altered expression of type II sodium/phosphate cotransporter in polycystic kidney disease. J Am Soc Nephrol 11: 1926-1932, 2000 1.64. Karbach U, Kricke J, Meyer-Wentrup F, Gorboulev V, Volk C, Loffing-Cueni D, Kaissling B, Bachmann S, Koepsell H: Localization of organic cation transporters OCT1 and OCT2 in rat kidney. Am J Physiol 279: F679-F687, 2000 1.65. Willam C, Koehne P, Jürgensen JS, Grafe M, Wagner KD, Bachmann S, Frei U, Eckardt KU: Tie2 receptor expression is stimulated by hypoxia and proinflammatory cytokines in human endothelial cells. Circ Res 87(5): 370-377, 2000 1.66. Weichert W, Paliege A, Provoost AP, Bachmann S: Upregulation of juxtaglomerular NOS1 and COX-2 precedes glomerulosclerosis in fawn-hooded hypertensive rats. Am J Physiol 280: F706-F714, 2001 1.67. Theilig F, Bostanjoglo M, Pavenstädt H, Grupp C, Holland G, Slosarek I, Gressner AM, Russwurm M, Koesling D, Bachmann S: Cellular distribution and function of soluble guanylyl cyclase in rat kidney and liver. J Am Soc Nephrol 12: 2209-2220, 2001 1.68. Câmpean V, Kricke J, Ellison DH, Luft F, Bachmann S: Localization of thiazide-sensitive Na+-Cl- cotransport and associated gene products in mouse DCT. Am J Physiol 281: F1028-F1035, 2001 1.69. Ketteler M, Westenfeld R, Gawlik A, Bachmann S, Frey A, Schönfelder G, Paul M, Distler A, de Heer E: Nitric oxide synthase isoform expression in acute versus chronic anti-Thy 1 nephritis. Kidney Int 61: 826-833, 2002 1.70. Theilig F, Câmpean V, Paliege A, Breyer M, Briggs JP, Schnermann J, Bachmann S: Epithelial COX-2 expression is not regulated by NO: Colocalization studies in rat and mouse renal cortex. Hypertension 39: 848-853, 2002 1.71. Rosenberger C, Mandriota S, Jürgensen JS, Wiesener MS, Hörstrup JH, Ratcliffe PJ, Frei U, Ratchliffe PJ, Maxwell PH, Bachmann S, Eckardt KU: Expression of hypoxia-inducible factor-1α and -2α in hypoxic and ischemic rat kidneys. J Am Soc Nephrol 13:1721-1732, 2002 1.72. Hilpert J, Wogensen L, Thykjaer T, Wellner M, Schlichting U, Orntoft F, Bachmann S, Nykjaer A, Willnow TE: Expression profiling confirms role of endocytic receptor megalin in renal vitamin D3 metabolism. Kidney Int 62(5): 1672-1681, 2002 1.73. Leheste JR, Melsen F, Wellner M, Jansen P, Schlichting U, Renner-Müller I, Andreassen TT, Wolf E, Bachmann S, Nykjaer A, Willnow TE: Hypocalcemia and osteopathy in mice with kidney-specific megalin gene defect. FASEB J 17(2). 247-249, 2003 1.74. Wiesener MS, Jürgensen JS, Rosenberger C, Scholze C, Hörstrup JH, Warnecke C, Mandriota S, Bechmann I, Frei UA, Pugh CW, Ratcliffe PJ, Bachmann S, Maxwell PH, Eckardt KU: Widespread, hypoxia-inducible expression of HIF-2 in distinct cell populations of different organs. FASEB J 17(2): 271-273, 2003 1.75. Schmitt R, Ellison DH, Klussmann E, Bachmann S: Renal expression of sodium transporters and aquaporin-2 in hypothyroid rats. Am J Physiol 284: F1097-F1104, 2003 1.76. Stubbe J, Jensen BL, Bachmann S, Morsing P, Skøtt O: Cyclooxygenase-2 contributes to elevated renin in the early postnatal period in rats. Am J Physiol 284(5): R1179-R1189, 2003 1.77. Câmpean V, Theilig F, Paliege A, Breyer M, Bachmann S: Key enzymes for renal prostaglandin synthesis: site-specific expression in rodent kidney (rat, mouse). Am J Physiol 285: F19-F32, 2003. 1.78. Deja M, Busch T, Bachmann S, Riskowsky K, Câmpean V, Wiedmann B, Schwabe M, Hell B, Pfeilschifter J, Falke KJ, Lewandowski K: Reduced nitric oxide in sinus epithelium of patients with radiologic maxillary sinusitis and sepsis. Am J Respir Crit Care Med 168: 281-286, 2003
1.79. Warnecke C, Griethe W, Weidemann A, Jürgensen JS, Willam C, Bachmann S, Ivaschchenko Y, Wagner I,
Frei U, Wiesener M, Eckardt KU: Activation of the hypoxia-inducible factor pathway and stimulation of angiogenesis by application of prolyl hydroxylase inhibitors. FASEB J 17(9): 1186-1188, 2003 1.80. Rosenberger C, Griethe W, Gruber G, Wiesener M, Frei U, Bachmann S, Eckardt KU: Cellular responses to hypoxia after renal segmental infarction. Kidney Int 64(3): 874-886, 2003
1.81. Schmitt R, Bachmann S: Impact of thyroid dysfunction on serum cystatin C. Kidney Int 64(3): 1139-1140, 2003

1.82. Gerlach JC, Mutig K, Sauer IM, Schrade P, Efimova E, Mieder T, Naumann G, Grunwald A, Pless G, Mas A,
Bachmann S, Neuhaus P, Zeilinger K: Use of primary human liver cells originating from discarded grafts in a bioreactor for liver support therapy and the prospects of culturing adult liver stem cells in bioreactors: a morphologic study. Transplantation 76: 781-786, 2003
1.83. Griethe W, Schmitt R, Jürgensen JF, Bachmann S, Eckardt KU, Schindler R: Bone morphogenic protein-4
expression in vascular lesions of calciphylaxis. J Nephrol 16(5): 728-732, 2003 1.84. Hocher B, Schwarz A, Slowinski T, Bachmann S, Pfeilschifter J, Neumayer HH, Bauer C: In-vivo interaction of nitric oxide and endothelin. J Hypertens 22(1):111-119, 2004 1.85. Madsen K, Stubbe J, Yang T, Skøtt O, Bachmann S, Jensen BL: Low endogenous glucocorticoid allows induction of kidney cortical cyclooxygenase-2 during postnatal rat development. Am J Physiol 286(1):F26-F37, 2004 1.86 Bachmann S, Schlichting U, Geist B, Mutig K, Petsch T, Bacic D, Wagner CA, Kaissling B, Biber J, Murer H, Willnow T: Kidney-specific inactivation of the megalin gene impairs trafficking of renal inorganic sodium phosphate-cotransporter (NaPi-IIa). J Am Soc Nephrol 15(4):892-900, 2004 1.87. Schmitt R, Kahl T, Mutig K, Bachmann S: Selectively reduced expression of thick ascending limb Tamm- Horsfall protein in hypothyroid kidneys. Histochem Cell Biol 121:319-327, 2004 1.88. Henn V, Edemir B, Stefan E, Wiesner B, Lorenz D, Theilig F, Schmitt R, Vossebein L, Tamma G, Beyermann M, Krause E, Herberg FW, Valenti G, Bachmann S, Rosenthal W, Klussmann E: Identification of a novel A-kinase anchoring protein 18 isoform and evidence for its role in the vasopressin-induced aquaporin-2 shuttle in renal principal cells. J Biol Chem 279(25):26654-26665, 2004 1.89. Tian W, Salanova M, Xu H, Lindsley JN, Oyama TT, Anderson S, Bachmann S, Cohen DM: Renal expression of osmotically responsive cation channel TRPV4 is restricted to water-impermeant nephron segments. Am J Physiol 287(1):F17-F24, 2004
1.90. Castrop H, Huang Y, Hashimoto S, Mizel D, Hansen P, Theilig F, Bachmann S, Deng C, Briggs J,
Schnermann J: Impairment of Tubuloglomerular Feedback Regulation of GFR in Ecto-5’-Nucleotidase/CD73-Deficient Mice. J Clin Invest 114(5): 634-642, 2004 1.91. Paliege A, Mizel D, Medina C, Pasumarthy A, Huang YG, Bachmann S, Briggs JP, Schnermann JB, Yang T: Inhibition of nNOS expression in the macula densa by COX-2 derived prostaglandin E2. Am J Physiol 287:F152-F159, 2004 1.92. Versen-Hoeynck F von, Syring C, Bachmann S, Moeller DE: The influence of different preservation and sterilisation steps on the histological properties of amnion allografts – light and scanning electron microscopic studies. Cell Tissue Bank 5(1): 45-56, 2004 1.93. Ordemann J, Jakob J, Braumann C, Kilian M, Bachmann S, Jacobi CA: Morphology of the rat peritoneum after carbon dioxide and helium pneumoperitoneum: a scanning electron microscopic study. Surg Endosc 18(9): 1389-1393, 2004 1.94. Jürgensen JS, Rosenberger C, Wiesener MS, Warnecke C, Hörstrup JH, Gräfe M, Philipp S, Griethe W, Maxwell PH, Frei U, MD; Bachmann S, Willenbrock R, Eckardt KU: Persistent induction of HIF-1alpha and -2alpha in cardiomyocytes and stromal cellsof ischemic myocardium. FASEB J 18(12): 1415-1417, 2004 1.95. Rosenberger C, Heyman SN, Rosen S, Shina A, Goldfarb M, Griethe W, Frei U, Reinke P. Bachmann S, Eckardt KU: Upregulation of HIF in experimental acute renal failure – evidence for a protective transcriptional response to hypoxia. Kidney Int 67: 531-542, 2005 1.96. Bachmann S, Mutig K, Bates J, Welker P, Gross V, Luft FC, Alenina N, Bader M, Thiele BJ, Prasadan K, Raffi HS, Kumar S: Renal effects of Tamm Horsfall protein (uromodulin) deficiency in mice. Am J Physiol 288(3): F559-F567, 2005 1.97. Kulaksiz H, Theilig F, Bachmann S, Gehrke SG, Rost D, Janetzko A, Cetin Y, Stremmel W: The iron- regulatory peptide hormone hepcidin: expression and cellular localization in the mammalian kidney. J Endocrinol 184(2): 361-370, 2005 1.98. Döring F, Schmitt R, Bernhardt WM, Klapper M, Bachmann S, Daniel H, Groneberg DA: Hypothyroidism induces expression of the peptide transporter PEPT2. Biol Chem 386(8): 785-790, 2005 1.99. Mao L, Zabel C, Wacker MA, Nebrich G, Sagi D, Schrade P, Bachmann S, Kowald A, Klose J:. Estimation of the mtDNA mutation rate in aging mice by proteome analysis and mathematical modeling. Exp Gerontol 41(1): 11-24, 2006 1.100. Bernhardt WM, Schmitt R, Rosenberger C, Münchenhagen PM, Gröne HJ, Frei U, Warnecke C, Bachmann S, Wiesener MS, Willam C, Eckardt KU: Expression of hypoxia-inducible transcription factors in developing human and rat kidneys. Kidney Int 69(1): 114-122, 2006 1.101. Paliege A, Parsumathy A, Mizel D, Yang T, Schnermann J, Bachmann S: Effect of apocynin treatment on renal expression of COX-2, NOS1, and renin in Wistar-Kyoto and spontaneously hypertensive rats. Am J Physiol 290(3):R694-R700, 2006 1.102. Pfab T, Thöne-Reineke C, Theilig F, Lange I, Witt H, Maser-Gluth C, Bader M, Stasch JP, Ruiza P, Bachmann S, Yanagisawa M, Hocher B: Diabetic endothelin B receptor-deficient rats develop severe hypertension and progressive renal failure. J Am Soc Nephrol 17: 1082-1089, 2006 1.103. Castrop H, Oppermann M, Weiss Y, Huang Y, Mizel D, Lu H, Germain S, Schweda F, Theilig F, Bachmann S, Briggs J, Kurtz A, Schnermann J: Reporter gene recombination in juxtaglomerular granular and collecting duct cells by a human renin promoter-Cre recombinase transgene. Physiol Genomics 25(2):277-285, 2006 1.104. Amstislavsky S, Welker P, Frühauf JH, Maslova L, Ivanova L, Jensen B, Markel AL, Bachmann S. Renal and endocrine changes in rats with inherited stress-induced arterial hypertension (ISIAH). Histochem Cell Biol 125:651-659, 2006 1.105. Gersch M, Mutig K, Bachmann S, Kumar S, Ouyang X, Johnson R: Is salt-wasting the long awaited answer to the hyperuricaemia seen in uromodulin storage diseases? Nephrol Dial Transplant 21(7): 2028-2029, 2006 1.106. Theilig F, Debiec H, Nafz B, Ronco P, Nüsing R, Seyberth W, Pavenstädt H, Bouby N, Bachmann S: Renal cortical regulation of COX-1 and functionally related products in early renovascular hypertension (rat). Am J Physiol 291: F987-F994, 2006 1.107. Oppermann M, Mizel D, Huang G, Li C, Deng C, Theilig F, Bachmann S, Briggs J, Schnermann J, Castrop H: Macula densa control of renin secretion and preglomerular resistance in mice with selective deletion of the B isoform of the Na,K,2Cl co-transporter. J Am Soc Nephrol 17: 2143-2152, 2006 1.108. Slevogt H, Seybold J, Tiwari KN, Hocke AC, Jonatat C, Dietel S, Hippenstiel S, Singer BB, Bachmann S, Suttorp N, Opitz B: Moraxella catarrhalis is internalized in respiratory epithelial cells by a trigger-like mechanism and initiates a TLR2- and partly NOD1-dependent inflammatory immune response. Cell Microbiol 9(3): 694-707, 2007 1.109. Welker P, Geist B, Frühauf JH, Salanova M, Groneberg DA, Krause E, Bachmann S: Role of lipid rafts in membrane delivery of renal epithelial Na+, K+-ATPase, thick ascending limb. Am J Physiol 292(3): R1328-R1337, 2007 1.110. Yang CL, Liu X, Paliege A, Zhu X, Bachmann S, Dawson DC, Ellison DH: WNK1 and WNK4 modulate CFTR activity. Biochem Biophys Res Commun 353(3): 535-540, 2007 1.111. Stefan E, Wiesner B, Baillie GS, Mollajew R, Henn V, Lorenz D, Furkert J, Santamaria K, Nedvetsky P, Hundsrucker C, Beyermann M, Krause E, Pohl P, Gall I, MacIntyre AN, Bachmann S, Houslay MD, Rosenthal W, Klussmann E: Compartmentalization of cAMP-dependent signaling by phosphodiesterase-4D is involved in the regulation of vasopressin-mediated water reabsorption in renal principal cells. J Am Soc Nephrol 18(1): 199-212, 2007 1.112. Merle U, Theilig F, Fein E, Gehrke S, Kallinowski B, Riedel HD, Bachmann S, Stremmel W, Kulaksiz H: Localization of the iron-regulatory proteins hemojuvelin and transferrin receptor 2 to the basolateral membrane domain of hepatocytes. Histochem Cell Biol 127(2): 221-226, 2007 1.113. Quaschning T, Voss F, Relle K, Kalk P, Vignon-Zellweger N, Pfab T, Bauer C, Theilig F, Bachmann S, Kraemer-Guth A, Wanner C, Theuring F, Galle J, Hocher B: Lack of endothelial nitric oxide synthase promotes endothelin-induced hypertension: Lessons from Endothelin-1 transgenic/endothelial nitric oxide synthase knockout mice. J Am Soc Nephrol 18(3): 730-740, 2007 1.114. Theilig F, Kriz W, Jerichow T, Schrade P, Hähnel B, Willnow T, Le Hir M, Bachmann S: Abrogation of protein uptake through megalin-deficient proximal tubules does not safeguard against tubulo-interstitial injury. J Am Soc Nephrol 18: 1824-1834, 2007 1.115. Fischer A, Stuckas H, Gluth M, Russell TD, Rudolph MC, Beeman NE, Bachmann S, Umemura S, Ohashi Y, Neville MC, Theuring F: Impaired Tight Junction Sealing and Precocious Involution in Mammary Glands of PKN Transgenic Mice. J Cell Sci 120(13): 2272-2283, 2007 1.116. Mutig K, Paliege A, Kahl T, Jöns T, Müller-Esterl W, Bachmann S: Vasopressin V2 receptor expression along rat, mouse, and human renal epithelia with focus on TAL. Am J Physiol 293(4):F1166-F1177, 2007 1.117. N'Guessan PD, Vigelahn M, Bachmann S, Zabel S, Opitz B, Schmeck B, Hippenstiel S, Zweigner J, Riesbeck K, Singer BB, Suttorp N, Slevogt H. The UspA1 protein of Moraxella catarrhalis induces CEACAM-1-dependent apoptosis in alveolar epithelial cells.J Infect Dis 195(11): 1651-1660, 2007 1.118. Theilig F, Goranova I, Hirsch JR, Wieske M, Unsal S, Bachmann S, Veh RW, Derst C: Cellular localization of THIK-1 (K(2P)13.1) and THIK-2 (K(2P)12.1) K channels in the mammalian kidney. Cell Physiol Biochem 21(1-3): 63-74, 2008 1.119. Stößel A, Paliege A, Theilig F, Addabbo F, Waschke J, Patschan D, Goligorsky MS, Bachmann S: Indolent course of tubulointerstitial disease in a mouse model of sub-pressor, low-dose nitric oxide synthase inhibition. Am J Physiol 295(3): F17-F25, 2008 1.120. Welker P, Böhlick A, Mutig K, Salanova M, Kahl T, Schlüter H, Blottner D, Ponce-Coria J, Gamba G, Bachmann S: Renal Na-K-Cl cotransporter activity and vasopressin-induced trafficking are lipid raft-dependent. Am J Physiol 295(3): F559-F567, 2008 1.121. Tchekneva EE, Khuchua Z, Davis LS, Kadkina V, Dunn SR, Bachmann S, Ishibashi K, Rinchik EM, Harris RC, Dikov MM, Breyer MD: Single amino acid substitution in aquaporin 11 causes renal failure. J Am Soc Nephrol 19(10):1955-1964, 2008 1.122. Welker P, Krämer S, Neumayer H, Bachmann S, Amann K, Peters H: Increased mast cell number in human hypertensive nephropathy. Am J Physiol 295(4): F1103-F1109, 2008 1.123. Duning K, Schurek EM, Schlüter M, Bayer M,Reinhardt HC, Schwab A, Schäfer L, Benzing T, Schermer B, Saleem MA, Huber TB, Bachmann S, Kremerskothen J, Weide T, Pavenstädt H: KIBRA modulates directional migration of podocytes. J Am Soc Nephrol 19(10):1891-1903, 2008 1.124. Rosenberger C, Goldfarb M, Shina A, Bachmann S, Frei U, Eckardt KU, Schrader T, Rosen S, Heyman SN: Evidence for sustained renal hypoxia and transient hypoxia adaptation in experimental rhabdomyolysis-induced acute kidney injury. Nephrol Dial Transplant 23(4):1135-1143, 2008 1.125. Kim SM, Theilig F, Qin Y, Cai T, Mizel D, Faulhaber-Walter R, Hirai H, Bachmann S, Briggs JP, Notkins AL, Schnermann JB: Dense core vesicle proteins IA-2 and IA-2beta affect renin synthesis and secretion through the beta-adrenergic pathway. Am J Physiol Renal Physiol 296(2): F382-F389, 2009 1.126. Gadau J, Peters H, Kastner C, Kühn H, Nieminen-Kelhä M, Khadzhynov D, Krämer S, Castrop H, Bachmann S, Theilig F: Mechanisms of tubular volume retention in immune-mediated glomerulonephritis. Kidney Int 75(7):699-710, 2009 1.127. Erb MA, Claus T, Hartrumpf M, Bachmann S, Albes JM: The use of Tachosil surgical patch or fibrin glue in coronary artery surgery does not affect quality of anastomosis or provoke postoperative adhesions in pigs. Eur J Cardiothorac Surg 36(4): 703-707, 2009 1.128. Kastner C, Pohl M, Sendeski M, Patzak A, Stange G, Wagner CA, Jensen B , Bachmann S, Theilig F: Effects of receptor-mediated endocytosis and tubular protein composition on volume retention in experimental glomerulonephritis. Am J Physiol 296(4): F902-F911, 2009 1.129. Schmelzer E, Mutig K, Schrade P, Bachmann S, Gerlach JC, Zeilinger K: Effect of human patient plasma ex vivo treatment on gene expression and progenitor cell activation of primary human liver cells in multi-compartment 3D perfusion bioreactors for extra-corporeal liver support. . Biotechnol Bioeng 103(4): 817-827, 2009 1.130. Paliege A, Rosenberger C, Bondke A, Sciesielski L, Shina A, Heyman SN, Flippin LA, Arend M, Klaus SJ, Bachmann S: Hypoxia-inducible factor-2alpha-expressing interstitial fibroblasts are the only renal cells that express erythropoietin under hypoxia-inducible factor stabilization. Kidney Int 77: 312-318, 2010 1.131. Trusch M, Böhlick A, Hildebrand D, Lichtner B, Bertsch A, Kohlbacher O, Bachmann S, Schlüter H: Application of displacement chromatography for the analysis of a lipid raft proteome. J Chromatogr B Analyt Technol Biomed Life Sci 878(3-4): 309-314, 2010 1.132. Park HC, Yasuda K, Ratliff B, Stößel A, Sharkovska Y, Yamamoto I, Jasmin JF, Bachmann S, Lisanti MP, Chander PN, Goligorsky MS: Post-obstructive regeneration of the kidney is derailed, when surge in renal stem cells during the course of unilateral ureteral obstruction is halted. Am J Physiol 298(2): F357-F364, 2010 1.133. Stößel A, Himmerkus N, Bleich M, Bachmann S, Theilig F: Connexin 37 is localized in renal epithelia and responds to changes in dietary salt intake. Am J Physiol 298(1): F216-F223, 2010 1.134. Mutig K, Saritas T, Uchida S, Kahl T, Borowski T, Paliege A, Böhlick A, Bleich M, Shan Q, Bachmann S: Short-term stimulation of the thiazide-sensitive Na+,Cl--cotransporter by vasopressin involves phosphorylation and membrane translocation. Am J Physiol Renal Physiol 298(3): F502-F509, 2010 1.135. Rajab A, Straub V, McCann LJ, Seelow D, Varon R, Barresi R, Schulze A, Lucke B, Lützkendorf S, Karbasiyan M, Bachmann S, Spuler S, Schuelke M: Fatal Cardiac Arrhythmia and Long-QT Syndrome in a New Form of Congenital Generalized Lipodystrophy with Muscle Rippling (CGL4) Due to PTRF-CAVIN Mutations. PLoS Genetics 6(3): e1000874, 2010 1.136. Gajera C, Emich H, Lioubinski O, Christ A, Beckervordersandforth-Bonk R, Yoshikawa K, Bachmann S, Christensen EI, Götz M, Kempermann G, Peterson AS, Willnow TE, Hammes A: LRP2 in ependymal cells regulates BMP signaling in the adult neurogenic niche. J Cell Sci 123(Pt 11): 1922-1930, 2010 1.137. Reiche J, Theilig F, Rafiqi FH, Militz D, Mutig K, Todiras M, Christensen EI, Ellison DH, Bader M, Nykjaer A, Bachmann S, Alessi D, Willnow TE. SORLA/SORL1 functionally interacts with SPAK to control renal activation of Na+-K+-Cl- cotransporter 2. Mol Cell Biol 30(12): 3027-3037, 2010 1.138. Polzin D, Kaminski HJ, Kastner C, Wang W, Krämer S, Gambaryan S, Russwurm M, Peters H, Wu Q, Vandewalle A, Bachmann S, Theilig F: Decreased renal corin expression contributes to sodium retention in proteinuric kidney diseases.Kidney Int 78(7): 650-659, 2010 1.139. Nedvetsky PI, Tabor V, Tamma G, Beulshausen S, Skroblin P, Kirschner A, Mutig K, Boltzen M, Petrucci O, Vossenkämper A, Wiesner B, Bachmann S, Rosenthal W, Klussmann E. Reciprocal Regulation of Aquaporin-2 Abundance and Degradation by Protein Kinase A and p38-MAP Kinase. J Am Soc Nephrol 21(10): 1645-1656, 2010 1.140. Schildroth J, Rettig-Zimmermann J, Kalk P, Steege A, Schmidt S, Fähling M, Sendeski M, Paliege A, Lai EY, Relle K, Bachmann S, Persson PB, Hocher B, Patzak A: Endothelin type A and B receptors in the control of afferent and efferent arterioles in mice. Nephrol Dial Transplant, 2010, in press

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The Metabolic Syndrome and Hypertension—R Kelishadi et al The Metabolic Syndrome in Hypertensive and Normotensive Subjects: The Isfahan Healthy Heart Programme R Kelishadi,1 MD , R Derakhshan,1 MD , B Sabet,1 MD , N Sarraf-Zadegan,1 MD , M Kahbazi,1 MD , GH Sadri,1 PhD ,AA Tavasoli,1 MD, S Heidari,1 MD , A Khosravi,1 MD , A Amani,1 MD , HR Tolouei,1 MD , A Bahonar,1 MD , AA RezaeiAshtiani,1

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