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Material safety data sheet

MEDISCA INC.
661 Route 3, Unit C, Plattsburgh, New York, 12901 Tel.: (800) 665-6334 Fax: (518) 563-5047 Material Safety Data Sheet
I - Product Identification:

Code:
Product Name:
Tretinoin, USP (Retinoic Acid)
CAS#: 302-79-4
Empirical Formula:
Chemical Name:
Uses:
Keratolytic; all trans-form also as antineoplastic. II - Toxicological Information:

Irritancy:
Adverse Effects:
Toxicity Data:
III - Physical Data:
Physical State:
Description:
Yellow to light orange, crystalline powder. Solubility:
Insoluble in water; slightly soluble in alcohol, and in chloroform. Other Physical Properties:
USP Specifications:

Identification<197M><197U>: Conforms to the std tests (A,B) Loss on drying<731>: Residue on ignition<281>: <= 0.1% Preserve in tight containers, preferably under an atmosphere of an inert gas, protected from light. IV - Fire And Explosion Hazards:
Flammability:
Flash Point:
Extinguishing Media:
Water spray, carbon dioxide, dry chemical, or chemical foam. Fire-Fighting:
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. V - Reactivity Data:

Stability:
Incompatibility:
Hazardous Decomp. Products:
Hazardous Polymerization:
VI - Preventive Measures:

Preventive Measures:
Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Use only in a chemical hood. Personal Protective Equipment:
Chemical resistant gloves, chemical goggles, protective clothing. Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN149 approved respirator when necessary. Specific Engineering Controls:
Eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Spill & Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Waste Disposal:
Dispose of in a manner consistent with federal, state, and local regulations. Storage:
Preserve in tight containers, preferably under an atmosphere of an inert gas, VII - First Aid Measures:

Eyes:
Flush with copious amounts of water for 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin:
Wash with plenty of soap & water for 15 minutes while removing contaminated clothing and shoes. Get medical aid. Ingestion:
Get medical aid. Wash out mouth with water. TRETINOIN, USP (RETINOIC ACID)
JULY 2007
MEDISCA INC.
661 Route 3, Unit C, Plattsburgh, New York, 12901 Tel.: (800) 665-6334 Fax: (518) 563-5047 Inhalation:
Remove to fresh air. If not breathing, give A.R. If breathing is difficult, give oxygen. Get medical aid. NOTE: If victim is unconscious, never induce vomiting nor give liquids. Place victim in a stable side position and keep warm.

Ecological Data:
Hazardous Ingredients:
References:
TRETINOIN, USP (RETINOIC ACID)
JULY 2007

Source: http://www.msdsexplorer.com/PDFsFiles/7201.pdf

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