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Stevens_bio.doc (preview)
Contact Details :Centex Shrimp Biotechnology, Room 440Chalerm Prakiat Building 4th Floor, Faculty of Science, Mahidol UniversityRama VI Road Bangkok 10400, ThailandTel : 0-2201-5873 Fax : 0-2354-7344.
E-mail: Academic Position : Visiting ProfessorCentex Shrimp Biotechnology, Faculty of Science, Mahidol University Research Interest :- Chitosan microspheres for drug delivery and tissue engineering- Production of high quality chitosan- Product diversification of chitosan- Quality control of chitosan- Chitin oligomer chitin synthesis and fractionation- Chitin nanoparticles Collaborations and Networking (selection) : Collaboration with Universities and Institutes in Thailand Research collaboration with Universities in Singapore, Osaka, Gwangju (Korea), Nha Trang(VN) and Palmerstone (NZ) Committee member Asia Pacific Conferences on Chitin and Chitosan Bangkok (1996, 2002),Singapore (2004) and Busan Korea (2006). Co-organizer Asian Pacific Conference on Chitinand Chitosan in Yangon, Myanmar June 2008 Member of the EU consortium on Nano Bio Saccharides, a joint research program with 10prominent European laboratories including Universities of Muenster (Germany), Lyon(France) , Santiago de Compostela (Spain) and Aarhus (Denmark) Areas of Specialization :Medical and animal biotechnologyMolecular and cell biologyProduction chitin chitosan biopolymers from shrimp and crab shellApplication chitosan in agriculture, food, feed, cosmetics, medicineQuality control of chitin and chitosanPreparation of chitin and chitosan microparticles and microspheresResearch on cloning of chitin deacetylase in the yeast PichiaToxicology and occupational toxicology Previous Job Experiences :J. F. Kennedy Professor in Bioprocess Technology 1994-2003Asian Institute of Technology, Bangkok, ThailandCoordinator PhD and MSc program. Advisor of thesis research of PhD and MSc studentsduring 10 yearsResearch in biopolymers mainly on industrial aspects of chitosan from shrimp, on starch fromcassava and on DNA detection.
Division Director TNO Health Research Organization The Netherlands 1990-94Research programs in gene technology, genotoxicity, gerontology, primate research,radiobiology, neurotoxicology, preventive health care and cardiovascular biochemistry.
Director Medical Biological Laboratory TNOThe Netherlands 1978 -1990Research programs in microbiology, DNA technology, cell biology, (occupational) toxicology AIT Full Professor Bioprocess Technology Metabolism and enzyme regulation in bacteriaElucidation origin DNA replication in bacteriophage lambdaNeuron and myotube development in tissue culture Starch Institute Changchun China FAO 1997Biotech in Organic farming APO, Hanoi 2003Nha Trang University of Fisheries Vietnam Japanese Society for Chitin ChitosanThai C hitin and Chitosan Consultancy GroupDutch Governmental Steering Committees on Industrial and Medical BiotechnologyEditor Journal GeneAcademic Board of University of RotterdamChair Committee for Molecular Biology, University of Amsterdam Chitosan-Alginate Multilayer Beads for Gastric Passage and Controlled Intestinal Release ofProteinsAnil K. Anal, Deepak Bhopatkar, Seiichi Tokura, Hiroshi Tamura and Willem F. StevensDrug Dev Ind Pharm (2003) 29, 713-724 Characterization of Decrystallized Chitosan and its Application in Biosorption of TextileDyes.
Trung, Trang Si, Ng Chuen How and Willem F. StevensBiotechnology Lett. (2003) 25: 1185-1190.
Quantification and Characterization of Insoluble Chitinous Materials in Viscous ChitosanSolutions.
Hein San, Ng Chuen How and Willem F. StevensBiotechnology Lett.(2003) 25: 863-868.
Genetically Modified Soybeans: False-Positive Detection in Fermented Natural Soybean(Tempe)Budi Prakoso, Sunee Nitisinprasert and Willem F. StevensBiotechnology Lett (2003) 25 1485-1490 Chitosan Membrane as a Wound Healing Dressing: Characterization and ClinicalApplicationsAbul Kalam Azad, Niwet Sermsintham, S. Chandrkrachang and Willem F. StevensJ. Biomed Mat. Res. 69B (2004) 216-222 Effect of Urea on Fungal Chitosan Production in Solid Substrate FermentationNwe, Nitar and Willem F. StevensProcess Biochemistry. 39 (2004) 1639-1642 Salt and pH Tolerance of Lactobacillus plantarum Strains for their use as Starters for Seafoodby-products FermentationRao, M. S., Jean-Pierre Guyot, Jose Pintado and Willem F. StevensBioresources Technology 94 (2004) 331-337 Transdermal Delivery by a Chitosan MembraneWah Wah Thein-Han and Willem F. StevensDrug Development and Industrial Pharmacy 30/4 (2004) 397-404 Improved Chitin Production by Pretreatment of Shrimp ShellsKyaw Nyein Aye and Willem F. StevensJ. Chem. Technol. and Biotechnol. (2004) 79: 421-425 Chitosan as a surface sizing agent for offset printing paperLertsutthiwong, P., Nazhad, M. M., Chandrkrachang, S. and Stevens, W.F.
Appita Journal (2004) 274-280 Expression of Chitin Deacetylase from Colletotrichum lindemutheanum in Pichia pastoris:Purification and Characterization.
Shrestha, B., Blondeau, K., Stevens, W.F., and Le Hegarat, F.
Protein Expression and Purification 38 (2004) 196-204 Chitin and Chitosan: Production and Application ResearchAsian Institute of Technology 1994 – 2004Willem F. StevensJ. Metals, Materials and Minerals 15 (2005) 75-83 Chitosan Alginate Multilayer Beads for Controlled Release of AmpicillinAnil Kumar Anal and Willem F. StevensInternational Journal of Pharmaceutics 290 (2005) 45-50 Ionotrophic Alginate Beads for Controlled Intestinal Protein Delivery: Effect of Chitosan andBarium Counterions on Entrapment and Release.
Bhopatkar,D., Anil Kumar Anal and Willem F. StevensJournal of Microencapsulation 22-1 (2005) 91-100 Chitin production by Lactobacillus fermentation of shrimp waste in a drum reactor and itschemical conversion to chitosanMukku Shrinivas Rao and Willem F. StevensJ. of Chem Techn and Biotechnology 80 (2005) in press Functional characteristics of shrimp chitosan and its membranes as affected by the degree ofdeacetylationTrang Si Trung, Wah Wah Thein-Han, Nguyen Thi Qui, Chuen-How Ng and Stevens, WillemF.
Bioresources Technology 97 (2006) 659-663 Peripheral Enzymatic Deacetylation of Regenerated Chitin ParticlesKyaw Nyein Aye, Renuka Karuppuswamy, Tangir Ahamed and Willem F. StevensBioresource Technology 97 (2006) 577-582 Production of N-acetyl chitobiose from various chitin substrates using commercial enzymesParaman Ilankovan, San Hein,Ng Chuen How,Trang Si Trung Willem F. StevensCarbohydrate Polymers 63 (2006) 245-250 Chuen-How Ng, San Hein, Suwalee Chandrkrachang and Willem F. Stevens.
Evaluation of an Improved acid hydrolysis-HPLC Assay for the Acetyl Content measurementin Chitin and ChitosanJournal of Biomedical Materials Research Part B: Applied Biomaterials 76B (2006) 155-160 Ionotropic cross-linked chitosan microspheres for controlled release of ampicillinAnil K. Anal, Willem F. Stevens, Carmen Remuñán-LópezInternational Journal of Pharmaceutics 312 (2006) 166-173 Optimum Parameters for Production of Chitin and Chitosan from Squilla (S. empusa)Mukku Shrinivas Rao, Kyaw Aye Nyein, Trang Si Trung and Willem F. StevensJournal of Applied Polymer Science 103 (2006) 3694-3700 Optimization of solid substrate fermentation for the production of fungal chitosan Nitar New and Willem F. StevensKorean Journal of Chitin Chitosan 11 (2006) 11-15 Fermentation of shrimp biowaste under different salt concentrations withamylolytic and non-amylolytic Lactobacillus strains for chitin productionMukku Shrinivas Rao and Willem F. StevensFood Technology and Biotechnology (2006) in the press Production of high quality chitin and chitosan from preconditioned shrimp shellsNguyen Van Toan, Chuen-How Ng, Kyaw Nyein Aye, Trung Si Trang and Willem F. StevensJ. of Chem Techn and Biotechnology 81 (2006) 1113-1118 Nwe, N and Stevens, W. F.
Optimization of Solid Substrate Fermentation for Production of Fungal Chitosan, Journal ofChitin Chitosan, 11 (2006) 11-15.
Nwe, N., Stevens, W. F, Tokura, S. and Tamura, H.
Fungal Chitosan Production on Sweet Potato,Chitin and Chitosan Research, 12 (2006) 118-119.
Nge, K. L., Nwe, N., Chandrkrachang, S and Stevens, W. F.
Chitosan as growth stimulator in orchid tissue culturePlant Science Journal, 170, 6 (2006) 1185-1190.
Shipin, O.V.S., EE, S.H.L.,Hiemchaisri, C.C.,Iwattanakom, W.W., Hosh, G.C.G., Anceno, A.
J. and Stevens, W.F.
Piggery Wastewater Treatment in a Tropical Climate: Biological and Chemical TreatmentOptionsEnvironmental Technology 28 (2007) 329-337 Distribution of D-glucosamine moieties in heterogeneously deacetylated cuttlefish chitin.
Chuen-How Ng, San Hein, Kozo Ogawa, S. Chandrkrachang, Willem F. StevensCarbohydrate Polymers (2007) published on line.


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