Publicatielijst 2005
Craen AJM de, Westendorp RGJ. Het gebruik van leeftijd als variabele in klinisch wetenschappelijk onderzoek. Ned Tijdschr Geneesk 2005,149:2958-2963.
Schoenmaker M, de Craen AJM, de Meijer PHEM, Beekman M, Blauw GJ, Slagboom PE, Westendorp RGJ, Evidence of genetic enrichment for exceptional survival using a family approach: The Leiden Longevity Study. Eur J Human Genetics 2006; 14: 79-84
Kamper AM, Westendorp RGJ. Ziekenhuisopnamen zijn bij bejaarden niet langduriger en frequenter dan bij jongeren. (Referaat). Ned Tijdschr Geneesk 2005; 149: 155-156.
Van der Flier, WM, van der Vlies AE, Weverling-Rijnsburger AWE, de Boer NL, Admiraal-Behloul F, Bollen ELEM, Westendorp RGJ, van Buchem MA, Middelkoop HAM. MRI measures and progression of cognitive decline in nondemented elderly attending a memory decline. Int.J Geriatric Psychiatry 2005; 11: 1060-1066.
Stott DJ, MacIntosh G, Lowe GDO, Rumley A, McMahon AD, Langhorne P, Tait RC, O'Reilly DS, Spilg EG, MacDonald JB, Macfarlane PW, Westendorp RGJ. Randomized controlled trial of homocysteine-lowering vitamin treatment in elderly patients with vascular disease. Am J Clin Nutrition 2005; 82:1320-1326.
Packard CJ, Ford I, Robertson M, Shepherd J, Blauw GJ, Murphy MB, Bollen ELEM, Buckley BM, Cobbe SM, Gaw A, Hyland M, Jukema W, Kamper AM, Macfarlane PW, Perry IJ, Stott DJ, Sweeney BJ, Twomey C, Westendorp RGJ for the PROSPER Study Group. Plasma, lipoproteins and apolipoproteins as predictors of cardiavascular risk and treatment benefit in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER). Circulation 2005; 112: 3058-3065.
Spilt A, Weverling-Rijnsburger AWE, Middelkoop HAM, van der Flier WM, Gussekloo J, de Craen AJM, Bollen ELEM, Blauw GJ, van Buchem MA, Westendorp RGJ. Late-onset dementia: structural brain damage and total cerebral blood flow. Radiology 2005; 236: 990-995.
Gussekloo J, De Craen AJM, Oduber C, van Boxtel MPJ, Westendorp RGJ. Sensory impairment and cognitive function in oldest-old subjects. The Leiden 85-plus Study. Am J Geriatric Psychiatry 2005;13: 781-786.
Bootsma-van der Wiel A, de Craen AJM, Van Exel E, Macfarlane PW, Gussekloo J, Westendorp RGJ. Association between chronic diseases and disability in elderly subjects with high and low income: the Leiden 85-plus Study. Eur J Public Health 2005; 15: 494-497.
Martin-Ruiz CM, Gussekloo J, van Heemst D, von Zglinicki T, Westendorp RGJ. Telomere length in white blood cells is not associated with morbidity or mortality in the oldest old: a population-based study. Aging Cell 2005;4:287-90.
Mooijaart SP, Brandt BW, Baldal EA, Pijpe J, Kuningas M, Beekman M, Zwaan BJ, Slagboom PE, Westendorp RGJ, van Heemst D. C. elegans DAF-12, nuclear hormone receptors and human longevity and disease at old age. Aging Research Reviews 2005; 4: 351-371.
Ten Dam VH, Box FMA, de Craen AJM, van den Heuvel DMJ, Bollen ELEM, Murray HM, van Buchem MA, Westendorp RGJ, Blauw GJ; Prosper Study group. Lack of effect of pravastatin on cerebral blood flow or parenchyma volume loss in elderly at risk for vascular disease. Stroke 2005;36:1633-6.
Vinkers DJ, Stek ML, van der Mast RC, de Craen AJM, Le Cessie S, Jolles J, Westendorp RGJ, Gussekloo J. Generalized atherosclerosis, cognitive decline, and depressive symptoms in old age. Neurology 2005;65:107-112.
Ten Dam VH, Van den Heuvel DMJ, Bollen ELEM, Van Buchem MA, Westendorp RGJ, Blauw GJ. Effect of pravastatin on cerebral infarcts and white matter lesions. Neurology 2005; 64: 1807-1809.
Mooijaart SP, Gussekloo J, Frölich M, Jolles J, Stott DJ, Westendorp RGJ, de Craen AJM. Homocysteine, vitamin B12, and folic acid and risk of cognitive decline in old age. The Leiden 85-plus Study. Am J Clin Nutr 2005; 82: 866-71.
Van der Flier WM, Middelkoop HAM, Weverling-Rijnsburger AWE, Admiraal-Behloul F, Bollen ELEM, Westendorp RGJ, van Buchem MA. Neuropsychological correlates of MRI measures in the continuum of cognitive decline at old age. Dementia geriatric cogn disord, 2005; 20: 82-88.
Endeman H, Heeffer L, Holleman F, Westendorp RGJ, Hoekstra JBL. Influence of old age on survival after prolonged mechanical ventilation. Eur J Intern Med 2005;16:116-119.
Brakefield PM, Gems D, Cowen T, Christensen K, Grubeck-Loebenstein B, Keller L, Oeppen J, Rodriques-Pena A, Stazi MA, Tatar M, Westendorp RGJ. What are the effects of maternal and pre-adult environments on ageing in humans, and are there lessons from animal models? Mech Ageing Dec 2005;126:431-8.
Spilt A, Geeraedts T, de Craen AJM, Westendorp RGJ, Blauw GJ, van Buchem MA. Age-related changes in normal appearing brain tissue and white matter hyperintensities: more of the same or something else? Am J Neuroradiol 2005;26:725-729.
Brandt BW, Zwaan BJ, Beekman M, Westendorp RGJ, Slagboom PE. Shuttling between species for pathways of lifespan regulation: a central role for the vitellogenin gene family? BioEssays 2005;27:339-346.
Van Heemst D, Mooijaart SP, Beekman M, Schreuder J, de Craen AJM, Brandt BW, Slagboom PE, Westendorp RGJ. Variation in the human TP53 gene affects old age survival and cancer mortality. Exp Gerontology 2005;40:11-5.
Gussekloo J, de Craen AJM, Westendorp RGJ. Thyriod status and survival in old age. (Reply) JAMA 2005;293:1447-1448.
Van Bemmel T, Westendorp RGJ. Het maligne neurolepticasyndroom bij gebruik van risperidon. Ned Tijdschr geneeskd 2005;149:608.
Van Heemst D, Beekman M, Mooijaart SP, Heijmans BT, Brandt BW, Zwaan BJ, Slagboom PE, Westendorp RGJ. Reduced insulin/IGF-1 signalling and human longevity. Aging Cell, 2005;4:79-85.
de Craen AJM, Posthuma D, Remarque EJ, van den Biggelaar AHJ, Westendorp RGJ, Boomsma DI. Heritability estimates of innate immunity: an extended twin study. Genes Immun 2005;6:167-170.
de Craen AJM, Gussekloo J, van der Mast RC, le Cessie S, Lemkes JW, Westendorp RGJ. Seasonal mood variation in the elderly: the Leiden 85-plus Study. Int J Ger Psychiatry 2005;20:269-273.
Westendorp RGJ, Wimmer C. Linking early development with ageing: towards a new research agenda. Mech Ageing Dev 2005;126:419-420.
Van Bemmel T, Vandenbroucke JP, Westendorp RGJ, Gussekloo J. In an observational study elderly patients had een increased risk of falling due to home hazards. The Leiden 85-plus study. J Clin Epid 2005;58:63-67.
Kirkwood TBL, Feder M, Finch CE, Franceschi C, Globerson A, Klingenberg CP, LaMarco K, Omholt S, Westendorp RGJ. What accounts for the wide variation in life span of genetically identical organisms reared in a constant environment? Mech Ageing Dev 2005;126:439-443.
De Craen AJM, Gussekloo J, Vrijsen B, Westendorp RGJ. Meta-analysis of nonsteroidal anti-inflammatory drug use and risk of dementia. Am J Epid 2005;161:114-120.
Stek ML, Gussekloo J, Beekman ATF, van der Mast RC, Westendorp RGJ. Is depression in old age fatal only when people feel lonely? Am J Psychiatry, 2005; 162: 178-180.
P lease mail to:Office of Admission Amherst College PO Box 5000 i n s t r u c t io n s amherst College looks, above all, for men and women of intellectual promise who have demonstrated quali-ties of mind and character that will enable them to take full advantage of our curriculum. We seek qualified applicants from different races, classes and ethnic groups — students whose several perspectiv
Impact of ADHD and Its Treatment on Substance Abuse in Adults Timothy E. Wilens, M.D. Attention-deficit/hyperactivity disorder (ADHD) is a risk factor for substance abuse in adults. Ad-ditional psychiatric comorbidity increases this risk. ADHD is associated with different characteristicsof substance abuse: substance abuse transitions more rapidly to dependence, and lasts longer in adults