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Ministério da Saúde FIOCRUZ Fundação Oswaldo Cruz Instituto Oswaldo Cruz Artigos científicos publicados pelo Programa de Pós-graduação Stricto sensu
em Biologia Parasitária do Instituto Oswaldo Cruz (IOC/Fiocruz) em 2013
1. AMARAL, S.S., OLIVEIRA, A.G., MARQUES, P.E., QUINTAO, J.L., PIRES, D.A., RESENDE, R. R., SOUSA, B.R., MELGACO, J.G., PINTO, M.A., RUSSO, R.C., GOMES, A.K., ZANIN, R.F., ANDRADE, L.M., PEREIRA, R.V., BONORINO, C., SORIANI, F.M., LIMA, C.X., CARA, D.C., TEIXEIRA, M.M., LEITE, M. F., MENEZES, G. B. 2013. Altered responsiveness to extracel ular ATP enhances acetaminophen hepatotoxicity. CELL COMMUN SIGNAL, v. 11, p. 10.1186/1478-81. 2. ARAUJO, V., BOITE, M., CUPOLILLO, E., JANSEN, A.M., ROQUE, A. 2013. Mixed infection in the anteater Tamandua tetradactyla (Mammalia: Pilosa) from Pará State, Brazil: Trypanosoma cruzi, T. rangeli and Leishmania infantum. Parasitology (London. Print), v. 140, p. 455-460. 3. ASTRO, M.G., NOGUEIRA, F.B., NOGUEIRA, R.M.R., LOURENCO-DE- OLIVERIA, R., DOS SANTOS, F.B. 2013. Genetic variation in the 3' untranslated region of dengue virus serotype 3 strains isolated from mosquitoes and humans in Brazil. Virology Journal, v. 10, p. 3. 4. BARROSO, D.E., CASTIÑEIRAS, T.M.P.P., CABRAL, A.C., VICENTE, A.C.P., REBELO, M.C., CERQUEIRA, E.O., TULENKO, M.M., MARSH, J.W., KRAULAND, M.G., HARRISON, L.H. 2013. Neisseria meningitidis ST-11 clonal complex bearing capsule serogroups B, C, or W in Brazil. The Journal of Infection, v. 57, p. 324-331. 5. BELINATO, T.A., MARTINS, A.J., LIMA, J.B.P., VALLE, D. 2013. Effect of triflumuron, a chitin synthesis inhibitor, on Aedes aegypti, Aedes albopictus and Culex quinquefasciatus under laboratory conditions. Parasites & Vectors, v. 6, p. 6. BRITO, L.P., LINSS, J.G.B., LIMA-CAMARA, T.N., BELINATO, T.A., PEIXOTO, A.A., LIMA, J.B. P., VALLE, D., MARTINS, A.J. 2013. Assessing the Effects of Aedes aegypti kdr Mutations on Pyrethroid Resistance and Its Fitness Cost. Plos 7. CALABRESE, K.S., SILVA, L.S., HARDOIM, D.J., SOUZA, C.S.F., ABREU-SILVA, A.L. 2013. Ocular experimental leishmaniasis in C57BL/10 and BALB/c mice induced by Leishmania amazonensis infection. Experimental Parasitology, v. 133, p. 156-161. 8. CALGUA, B., FUMIAN, T.M., RUSINOL, M., RODRIGUEZ-MANZANO J., MBAYED, V., BOFFIL-MAS, S., MIAGOSTOVICH, M.P., GIRONÉS, R. 2013. Ministério da Saúde FIOCRUZ Fundação Oswaldo Cruz Instituto Oswaldo Cruz Detection and quantification of classic and emerging viruses by skimmed-milk flocculation and PCR in river water from two geographical areas. Water Research (Oxford), v. 47, p. 2797-2810. 9. CASTRO, M.G., NOGUEIRA, F.B., NOGUEIRA, R.M., LOURENÇO-DE-OLIVEIRA, R. SANTOS, F.B. 2013. Genetic variation in the 3' untranslated region of dengue virus serotype 3 strains isolated from mosquitoes and humans in Brazil. Virology Journal, v. 10, p. 3. 10. CHAHAD-EHLERS, S., GENTILE, C., LIMA, J.B.P., PEIXOTO, A.A., BRUNO, R.V. 2013. Analysis of cycle Gene Expression in Aedes aegypti Brains by In Situ Hybridization. Plos One, v. 8, p. e52559. 11. CHUNG, A. W., SIELING, P. A., SCHENK, M., TELES, R. M. B., KRUTZIK, S. R., HSU, D. K., LIU, F.-T., SARNO, E. N., REA, T. H., STENGER, S., MODLIN, R. L., LEE, D. J. 2013. Galectin-3 Regulates the Innate Immune Response of Human Monocytes. The Journal of Infectious Diseases, v. 207, p. 947-956. 12. COSTA, M. J. F.S., PEIXOTO, M.L.P., CORRÊA, L.R., MELLO-SILVA, C. C. C., PINHEIRO, J. S., MOTA E. M., SOUZA, S. S., ANDRADE, Z., MALDONADO JR, A. 2013. Biological, biochemical and histopathological features related to parasitic castration of Biomphalaria glabrata infected by Schistosoma mansoni. Experimental Parasitology, v. 134, p. 228. 13. COVAS C.J.F., CARDOSO C.C., GOMES-SILVA A., SANTOS-OLIVEIRA J.R., DA- CRUZ A.M., MORAES M.O. 2013. Candidate gene case-control and functional study shows macrophage inhibitoryfactor (MIF) polymorphism is associated with cutaneous leishmaniasis. Cytokine, v. 61, p. 168-172. 14. DE OLIVEIRA RAMOS PEREIRA, L., BRANDÃO, A. 2013. An analysis of trypanosomatids kDNA minicircle by absolute dinucleotide frequency. Parasitology International (Print), v. 62, p. 397-403. 15. DE OLIVEIRA, R.B., SENGER, M.R., VASQUES, L.M., GASPAROTTO, J., DOS SANTOS, J.P.A., DE BITTENCOURT PASQUALI, M.A., MOREIRA, J.C.F., SILVA, F.P., GELAIN, D.P. 2013. Schistosoma mansoni infection causes oxidative stress and alters receptor for advanced glycation endproduct (RAGE) and tau levels in multiple organs in mice. International Journal for Parasitology, v. 43, p. 371-379. 16. DE PAULA SCALIONI, L., CRUZ, H.M., DE PAULA, V.S., CORRÊIA OLIVEIRA, J., TOURINHO DOS SANTOS, R., MOTTA-CASTRO, A.R.C., MURAT, P.G., VILLELA-NOGUEIRA, C.A., LEWIS-XIMENEZ, L.L., LAMPE, E., VILLAR, L.M. 2013. Importance of Col ection Methods and Stability of Oral Fluid Samples for Hepatitis B Surface Antigen Detection. Journal of Clinical Laboratory Analysis (Print), v. 27: 186-94. Ministério da Saúde FIOCRUZ Fundação Oswaldo Cruz Instituto Oswaldo Cruz 17. DE PAULA, V.S., WIELE, M., MBUNKAH, A. H., DANIEL, A. M., KINGSLEY, M. T., SCHMIDT-CHANASIT, J. 2013. Hepatitis E Virus Genotype 3 Strains in Domestic Pigs, Cameroon. Emerging Infectious Diseases (Online), v. 19, p. 686-688. 18. DE VASCONCELOS MELO, F.T., PEREIRA E SILVA, J., COSTA GONÇALVES, E., PENHA FURTADO, A., GIESE, E. G., GUERREIRO GIESE, E., SANTOS, C. P., NASCIMENTO SANTOS, J. 2013. Taxonomic status and redescription of the genus Brasicystis Thatcher, 1979 (Digenea: Didymozoidae). Parasitology International (Print), v. 62, p. 208-214. 19. DOS SANTOS, D.S., DUPPRE, N.C., SALES, A.M., NERY, J.A.C., SARNO, E.N., HACKER, M.A. 2013. Kinship and Leprosy in the Contacts of Leprosy Patients: Cohort at the Souza Araújo Outpatient Clinic, Rio de Janeiro, RJ, 1987-2010. Journal of Tropical Medicine, v. 2013, p. 1-8. 20. ERONE, M. J., VELAZQUEZ, G., ARIAS, A. R., CHAMORRO, G., COLUCHI, N., PIRMEZ, C., SAVINO, W., BARBEITO, L., ARTZ, E. 2013. Primera red SudAmericana de biomedicina. Investigación, educación y biotecnología aplicadas a la salud. Medicina (Buenos Aires), v. 73, p. 75. 21. FARIA, N.R.C., NOGUEIRA, R.M.R., DE FILIPPIS, A.M.B., NOGUEIRA, F.B., LIMA, M.R.Q., DOS SANTOS, F. B. 2013. Twenty Years of DENV-2 Activity in Brazil: Molecular Characterization and Phylogeny of Strains Isolated from 1990 to 2010. PLoS Neglected Tropical Diseases (Online), v. 7, p. e2095. 22. FELICIO, D. L. F ., DA SILVA, R.I., VIDAL, L. S., VON KRUGER, W. A., BRITTO, C., CARDOSO, M. A., CARDOSO, J. S., LEITAO, A. C., LAGE, C. 2013. Overexpression of Escherichia coli nucleotide excision repair genes after cisplatin-induced damage. DNA Repair (Print), v. 12, p. 63-72. 23. FERNÁNDEZ-SÁNCHEZ, F., MARÌN-MORAN, J. E., PINTO, Z. T., QUEIROZ, M.M.C., ESCALONA-ARRANZ, J. C. 2013. Evaluación de las condiciones de extracción por hidrodestilación-cohobación del aceite esencial del fol aje de Pinus caribaea Morelet var. caribaea (droga seca). Revista Cubana de Química, v. XXV, p. 100-108. 24. FUMIAN, T.M., VIEIRA, C.B., LEITE, J.P.G., MIAGOSTOVICH, M.P. 2013. Assessment of burden of virus agents in an urban sewage treatment plant in Rio de Janeiro, Brazil. Journal of Water and Health, v. 11, p. 110. 25. GALLER, R., FREIRE, M. S., JABOR, A. V., MANN, G. F. 2013. The Synergistic Effect of Combined Immunization with a DNA Vaccine and Chimeric Yel ow Fever/Dengue Virus Leads to Strong Protection against Dengue. Plos One, Brasil, Ministério da Saúde FIOCRUZ Fundação Oswaldo Cruz Instituto Oswaldo Cruz 26. GIBSON, G., SOUZA-SANTOS, R., BRASIL, P., PACHECO, A.G., CRUZ, OSWALDO G., HONÓRIO, N.A., KUBELKA, C., CARVALHO, M.S. 2013. From primary care to hospitalization: clinical warning signs of severe dengue fever in children and adolescents during an outbreak in Rio de Janeiro, Brazil. Cadernos de Saúde Pública (ENSP. Impresso), v. 29, p. 82-90. 27. GOMES, T. F., FREITAS, F. S. S., BEZERRA, C. M., LIMA, M. M., CARVALHO- COSTA F.A. 2013. Reasons for persistence of dwel ing vulnerability to Chagas disease (American trypanosomiasis): a qualitative study in northeastern Brazil. World Health & Population, v. 14, p. 4-11. 28. GOMES-SILVA A., VALVERDE, J. G., RIBEIRO-ROMÃO R.P., PLACIDO- PEREIRA, R.M., DA-CRUZ A.M. 2013. Golden hamster (Mesocricetus auratus) as an experimental model for Leishmania (Viannia) braziliensis infection. Parasitology (London. Print), v. 140, p. 771-779. 29. GRAS, C., SMITH, N., SENGMANIVONG, L., GANDINI, M., KUBELKA, C.F., HERBEUVAL, J.P. 2013. TRAIL protein localization in human primary T cel s by 3D microscopy using 3D interactive surface plot: A new method to visualize plasma membrane. Journal of Immunological Methods (Print), v. 387, p. 147-156. 30. IÑIGUEZ, A. M., ANDRADE, J., DAMATA, R., SANTOS, C. 2013. Genetic characterization of the blood-sucking nematodes Libyostrongylus dentatus and Libyostrongylus douglassii supports their different evolutionary history. Veterinary Parasitology (Print), v. 193, p. 193-199. 31. JAEGER, L.H., SOUZA, S.M.F.M., DIAS, O., IÑIGUEZ, A. M. 2013. Mycobacterium tuberculosis Complex in Remains of 18th 19th Century Slaves, Brazil. Emerging Infectious Diseases (Online), v. 19, p. 837-839. 32. JAEGER, L.H., TAGLIORETTI, V., DIAS JR, O. F., IÑIGUEZ, A. M. 2013. Paleoparasitological analysis of human remains from a European cemetery of the 17th-19th century in Rio de Janeiro, Brazil. International Journal of Paleopathology. on line. 33. JAEGER, L.H., TAGLIORETTI, V., FUGASSA, M.H., DIAS, O., NETO, J., IÑIGUEZ, A.M. 2013. Paleoparasitological results from XVIII century human remains from Rio de Janeiro, Brazil. Acta Tropica, v. 125, p. 282-286. 34. MACEDO, G. A., DE ARAUJO, J. M. G., SCHATZMAYR, H. G., COSTA, F. A. C., DE FILIPPIS, A. M. B., SANTOS, F. B. D., NOGUEIRA, R. M. R. 2013. Virological surveil ance for early warning of dengue epidemics in the State of Rio de Janeiro, Brazil. Transactions of the Royal Society of Tropical Medicine and Hygiene, v. Jan14, p. 1-6. Ministério da Saúde FIOCRUZ Fundação Oswaldo Cruz Instituto Oswaldo Cruz 35. MALDANER, F.R., ARAGÃO, F.J.L., SANTOS, F.B., FRANCO, O.L., ROCHA QUEIROZ LIMA, M., OLIVEIRA RESENDE, R., VASQUES, R.M., NAGATA, T. 2013. Dengue virus tetra-epitope peptide expressed in lettuce chloroplasts for potential use in dengue diagnosis. Applied Microbiology and Biotechnology, v. 39, p. 1-11. 36. MARIN, M.A., THOMPSON, C.C., FREITAS, F.S., FONSECA, E.L., ABODERIN, A.O., ZAILANI, S.B., QUARTEY, N.E., OKEKE, I.N., VICENTE, A.C.P. 2013. Cholera Outbreaks in Nigeria Are Associated with Multidrug Resistant Atypical El Tor and Non-O1/Non-O139 Vibrio cholerae. PLoS Neglected Tropical Diseases (Online), v. 7, p. e2049. 37. MARTINS, M.A., BONALDO, M.C., RUDERSDORF, R.A., PIASKOWSKI, S.M., RAKASZ, E.G., WEISGRAU, K.L., FURLOTT, J.R., EERNISSE, C.M., VELOSO DE SANTANA, M.G., HIDALGO, B., FRIEDRICH, T.C., CHIUCHIOLO, M.J., PARKS, C.L., WILSON, N.A., ALLISON, D.B., GALLER, R., WATKINS, D.I. 2013. Immunogenicity of Seven New Recombinant Yel ow Fever Viruses 17D Expressing Fragments of SIVmac239 Gag, Nef, and Vif in Indian Rhesus Macaques. Plos One, 38. MARTINS, R.M., MAIA, M.L.S., FARIAS, R.H.G., CAMACHO, L.A.B., FREIRE, M.S., GALLER, R., YAMAMURA, A.M.Y., ALMEIDA, L.F.C., LIMA, S.M.B., NOGUEIRA, R.M.R., SÁ, G.R., HOKAMA, D.A., DE CARVALHO, R., FREIRE, R.A.V., FILHO, E.P., LEAL, M.L.F., HOMMA, A. 2013. 17DD yel ow fever vaccine: A double blind, randomized clinical trial of immunogenicity and safety on a dose- response study. Human vaccines & immunotherapeutics, v. 9, p. 1-9. 39. MARTINS, Y. C., CLEMMER L., ORJUELA-SANCHEZ P., ZANINI, G. M., ONG, P. K., FRANGOS, J., CARVALHO, L. J. M. 2013. Slow and continuous delivery of a low dose of nimodipine improves survival and electrocardiogram parameters in rescue therapy of mice with experimental cerebral malaria. Malaria Journal 40. MORAES, A.C., AMADO L.A., DE PAULA, V. S. 2013. Detection of replication- defective hepatitis A virus. Memórias do Instituto Oswaldo Cruz (Impresso), v. 108, p. 36-40. 41. MOREIRA, O. C., RAMIREZ, J. D., VELAZQUEZ, E., MELO, M. F. A. D., FERREIRA, C. L., GUHL, F., SOSA-ESTANI, S., MARIN-NETO, J. A., MORILLO, C., BRITTO, C. 2013. Towards the establishment of a consensus real-time qPCR to monitor Trypanosoma cruzi parasitemia in patients with chronic Chagas disease cardiomyopathy: A substudy from the BENEFIT trial. Acta Tropica, v. 125, p. 23-31, 2013. 42. MOREIRA, V.L.C., GIESE, E.G., MELO, F.T.V. , SIMÕES, R.O., THIENGO, S.C., MALDONADO, A., SANTOS, J.N. 2013. Endemic angiostrongyliasis in the Brazilian Ministério da Saúde FIOCRUZ Fundação Oswaldo Cruz Instituto Oswaldo Cruz Amazon: Natural parasitism of Angiostrongylus cantonensis in Rattus rattus and R. norvegicus, and sympatric giant African land snails, Achatina fulica. Acta Tropica, v. 125, p. 90-97. 43. MORENO, M., BICKERSMITH, S., HARLOW, W., HILDEBRANDT, J., MCKEON, S.N., SILVA-DO-NASCIMENTO, T.F., LOAIZA, J.R., RUIZ, F., LOURENÇO-DE-OLIVEIRA, R., SALLUM, M.A.M., BERGO, E.S., FRITZ, G.N., WILKERSON, R.C., LINTON, Y.M., JURI, M.J., RANGEL, Y., PÓVOA, M.M., GUTIÉRREZ-BUILES, L.A., CORREA, M.M., CONN, J.E. 2013. Phylogeography of the neotropical Anopheles triannulatus complex (Diptera: Culicidae) supports deep structure and complex patterns. Parasites & Vectors, v. 6, p. 47. 44. NASCIMENTO, F.F., LAZAR, A., MENEZES, A.N., DURANS, A.M., MOREIRA, J.C., SALAZAR-BRAVO, J., D'ANDREA, P.S., BONVICINO, C.R. 2013. The Role of Historical Barriers in the Diversification Processes in Open Vegetation Formations during the Miocene/Pliocene Using an Ancient Rodent Lineage as a Model. Plos One, v. 8, p. e61924. 45. NEVES, A.P., PEREIRA, M.X.G., PETERSON, E.J., KIPPING, R., M.D., SILVA-JR, F.P., CARNEIRO, J.W.M., FARRELL, N.P. 2013. Exploring the DNA binding/cleavage, cel ular accumulation and topoisomerase inhibition of 2-hydroxy- 3-(aminomethyl)-1,4-naphthoquinone Mannich bases and their platinum(II) complexes. Journal of Inorganic Biochemistry, v. 119, p. 54-64. 46. NOGUEIRA, R.T., NOGUEIRA, A.R., PEREIRA, M.C.S., RODRIGUES, M.M., NEVES, P.C.C., GALLER, R., BONALDO, M.C. 2013. Recombinant Yel ow Fever Viruses Elicit CD8+ T Cel Responses and Protective Immunity against Trypanosoma cruzi. Plos One, v. 8, p. e59347. 47. OLIVEIRA-JR, F. O. R., ALVES, C. R., SILVA, F. S., CÔRTES, L. M. C., TOMA, L., BOUÇAS, R. I., AGUILAR, T., NADER, H. B., PEREIRA, M. C. S. 2013. Trypanosoma cruzi heparin-binding proteins present a flagel ar membrane localization and serine proteinase activity. Parasitology (Cambridge. Online), v. 140, p. 171-180. 48. PAVAN, M.G., MESQUITA, R.D., LAWRENCE, G., LAZOSKI, C., DOTSON, E., ABUBUCKER, S., MITREVA, M., RANDALL-MAHER, J., MONTEIRO, F.A. 2013. A nuclear single-nucleotide polymorphism (SNP) potential y useful for the separation of Rhodnius prolixus from members of the Rhodnius robustus cryptic species complex (Hemiptera: Reduvi dae). Infection, Genetics and Evolution (Print), v. 14, p. 426-433. 49. PETITO, R.B., AMADEU, T.P., PASCARELLI, B.M.O., JARDIM, M.R., VITAL, R.T., ANTUNES, S.L., SARNO, E.N. 2013. Transforming Growth Factor-β1 May Be a Ministério da Saúde FIOCRUZ Fundação Oswaldo Cruz Instituto Oswaldo Cruz Key Mediator of the Fibrogenic Properties of Neural Cel s in Leprosy. Journal of Neuropathology and Experimental Neurology, v. 72, p. 351-66. 50. PRADO T., GUILAYN W.C.P.B., GASPAR, A.M.C., MIAGOSTOVICH, M.P. 2013. The efficiency of concentration methods used to detect enteric viruses in anaerobical y digested sludge'. Memórias do Instituto Oswaldo Cruz (Impresso), v. 108, p. 77-83. 51. PRATT-RICCIO, L.R., PERCE-DASILVA, D.S., LIMA-JUNIOR, J.C., THEISEN, M., SANTOS, F., DANIEL-RIBEIRO, C.T., OLIVEIRA-FERREIRA, J., BANIC, D.M. 2013. Genetic polymorphisms in the glutamate-rich protein of Plasmodium. Memórias do Instituto Oswaldo Cruz (Online), v. 108, p. 1. 52. ROCHA, F.L., ROQUE, A.L.R. ARRAIS, R.C., SANTOS, J.P., LIMA, V.D., XAVIER, S.C.C., CORDEIR-ESTRELA, P., D'ANDREA, P.S., JANSEN, A.M. 2013. Trypanosoma cruzi TcI and TcII transmission among wild carnivores, smal mammals and dogs in a conservation unit and surrounding areas, Brazil. Parasitology (Cambridge. Online), v. 140, p. 160-170. 53. ROQUE, A. L. R., XAVIER, S. C. C., GERHARDT, M., SILVA, M. F., LIMA, V. S., DANDREA, P. S., JANSEN, A. M. 2013. Trypanosoma cruzi among wild and domestic mammals in different areas of the Abaetetuba municipality (Pará State, Brazil), an endemic Chagas disease transmission area. Veterinary Parasitology 54. SABOIA-VAHIA, L., BORGES-VELOSO, A., MESQUITA-RODRIGUES, C., CUERVO, P., DIAS-LOPES, G., BRITTO, C., DE BARROS SILVA, A.P., DE JESUS, J.B. 2013. Trypsin-like serine peptidase profiles in the egg, larval, and pupal stages of Aedes albopictus. Parasites & Vectors, v. 6, p. 50. 55. SANTOS, C. P., LOPES, K.C., COSTA, V.S., SANTOS, E.G.N. 2013. Fish-borne trematodosis: Potential risk of infection by Ascocotyle (Phagicola) longa (Heterophyidae). Veterinary Parasitology (Print), v. 193, p. 302-306. 56. SANTOS, E.G.N., COSTA, V.S., SANTOS, C. P. 2013. Does the trematode Centrocestus formosanus affect the locomotory activity of the mol usc Melanoides tuberculatus?. Parasites & Vectors, v. 6, p. 92. 57. SANTOS, E.G.N., SANTOS, C.P. 2013. Parasite-induced and parasite development-dependent alteration of the swimming behavior of fish hosts. Acta Tropica, p. 56-62. 58. SANTOS-OLIVEIRA J.R., REGIS E.G., GIACOIA-GRIPP C.B.W., VAALVERDE J.G., ALEXANDRINO-DE-OLIVEIRA P., LINDOSO J.A.L., GOTO H., OLIVEIRA-NETO M.P., GUERRA J., GRINSTESZJN B., JERONIMO S.M.B., MORGADO, M.G., DA-CRUZ, A.M. 2013. Microbial translocation induces an intense Ministério da Saúde FIOCRUZ Fundação Oswaldo Cruz Instituto Oswaldo Cruz proinflammatory response in visceral leishmaniasis patients co-infected with HIV-1. The Journal of Infectious Diseases, v. 208 p. 57-66. 59. SCALIONI, L.P., CRUZ, H. M., OLIVEIRA, J. C., PAULA, V., TOURINHO, R. S., MOTTA-CASTRO, A.R.C., MURAT, P. G., VILLELA-NOGUEIRA, C.A., LEWIS-XIMENEZ, L.L., LAMPE, E., VILLAR, L. M. 2013. Importance of Col ection Methods and Stability of Oral Fluid Samples for Hepatitis B Surface Antigen Detection. Journal of Clinical Laboratory Analysis (Print), v. 27, p. 186-94. 60. SILVEIRA, L.B., MARCHI-SALVADOR, D.P., SANTOS-FILHO, N.A., SILVA, F.P.,
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How has it come to pass that in fin-de-siècle America, where every child from preschoolonward can recite the ‘anti-drug’ catechism by heart, millions of middle- and upper-middle class children are being legally drugged with a substance so similar to cocainethat, as one journalist accurately summarized the science, ‘it takes a chemist to tell theRitalin® is a popular pharmaceutical th

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• Have your blood pressure HYPERTENSION (HIGH BLOOD HYPERTENSION (HIGH BLOOD PRESSURE: PRESSURE) checked three to four times a Current guidelines state that year; it should be less than normal blood pressure is less than World Wide estimates of individuals 130/80mm Hg. with hypertension are 1 billion Pre-hypertension is systolic blood people

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