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AVLOCLOR TABLETS
Indications
This medicine is to give some degree of protection against malaria in certain
countries. Some types of malaria require that you take more than one type of tablet, at
the same time, to help prevent malaria. Malaria prophylaxis is recommended for non
immune residents and travellers to malarious areas as these individuals have little or
no immunity to malaria and risk severe attacks. You should ask your doctor or
pharmacist if these are the right anti-malarials for the part of the world you are
visiting.
Directions
Adults: Two tablets taken once a week, on the same day each week. Children: The
following single dose taken once a week on the same day each week. 1-4 years Half a
tablet, 5-8 years one tablet, 9-14 years one and a half tablet. Adults and children: Start
1 week before exposure to risk and continue until 4 weeks after leaving the malarious
area. Swallow the tablet (or part tablet) whole with a drink of water. Take tablets on
the same day each week, if you miss a dose, take the dose as soon as you remember,
do not take two doses at the same time. If you are elderly it may be advisable for your
doctor to do some blood tests and possibly prescribe a different dose. If you take more
than your normal dose contact your doctor or nearest hospital urgently. Do not stop
taking your tablets even if you are feeling unwell, until 4 weeks after leaving the
malarious area, unless your doctor tells you
Ingredients
Each tablet contains Chloroquine Phosphate Ph. Eur. 250mg (equivalent of 155mg of
chloroquine base) The tablets contain a number of inactive ingredients which allow it
to be made, these are maize starch and magnesium stearate.
Warnings
Before taking your medicine tell your doctor or pharmacist if: you have ever had
problems with your liver or kidneys, you have ever been told you have porphyria or
anyone in your family has, Avloclor may cause severe symptoms if you drink alcohol,
you have epilepsy, or a history of convulsions, seizures, or fits, you have psoriasis (a
scaly condition of the skin), you are pregnant or suspect you are pregnant, you are
breast feeding (your baby will still need to be given anti-malarial treatment and you
should consult your doctor or pharmacist for appropriate advice). If you suffer from
any fever (high temperature) during or after visiting a country where malaria occurs,
you should contact your doctor immediately.
Side Effects
As with all medicines, undesirable events are sometimes experienced. When Avloclor
is used in the prevention of malaria, if used for a long time they can be serious. For
Avloclor these include: Headache, stomach upset, skin rash or itch, hair
discolouration or hair loss, blurring of vision or difficulty in focusing your eyes,
convulsions or fits, mood changes or other effects on behaviour, changes in your
blood which may make you bruise easily, get serious infections, feel very tired or
breathless or may give your skin and eyes a yellow colour (due to liver problem);
severe rash with peeling or blistering skin sometimes with ulceration of mucus
membranes (for example, the inside of your mouth and nose). Stop taking Avloclor
and contact your doctor immediately in the following situation: If you develop
difficulty in breathing with or without swelling of the face, lips tongue or throat which
may cause difficulty in swallowing. If you develop urticaria (itchy skin rash, nettle rah
or hives).

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