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Microsoft word - ampicillin disc.docx

Section 1 - Chemical Product and Company Identification MSDS Name: Ampicillin
Catalog Numbers: S70151A
6-(D(-)-alpha-Aminophenylacetamido)penicillanic acid; Ampicin;
Company Identification:

Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call:
Emergency Number:
For CHEMTREC assistance, call:
For International CHEMTREC assistance, call:
Section 2 - Composition, Information on Ingredients Chemical Name
Appearance: white to off-white solid.
Warning! Causes eye, skin, and respiratory tract irritation. May cause allergic respiratory
and skin reaction.
Target Organs: Respiratory system, eyes, skin.
Potential Health Effects
Eye: Causes eye irritation.
Skin: Causes skin irritation. May cause skin sensitization, an allergic reaction, which
becomes evident upon re-exposure to this material. May be harmful if absorbed through the
Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May be
harmful if swallowed. May cause serious or fatal hypersensitivity (anaphylactic) reactions in
Inhalation: Causes respiratory tract irritation. May cause allergic respiratory reaction. May
be harmful if inhaled.
Chronic: No information found.

Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally
lifting the upper and lower eyelids. Get medical aid.
Skin: Immediately flush skin with plenty of water for at least 15 minutes while removing
contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash
clothing before reuse.
Ingestion: Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk
or water. Get medical aid.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing,
give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Treat symptomatically and supportively.

General Information: As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a
fire, irritating and highly toxic gases may be generated by thermal decomposition or
Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or appropriate foam.
Flash Point: Not applicable.
Autoignition Temperature: Not applicable.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 2; Flammability: 0; Instability: 0

General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container.
Clean up spills immediately, observing precautions in the Protective Equipment section.
Avoid generating dusty conditions. Provide ventilation.

Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before
reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid
contact with skin and eyes. Keep container tightly closed. Avoid ingestion and inhalation.
Storage: Store in a cool, dry, well-ventilated area away from incompatible substances.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Facilities storing or utilizing this material should be equipped with
an eyewash facility and a safety shower. Use adequate ventilation to keep airborne
concentrations low.
Exposure Limits
Chemical Name
OSHA - Final PELs

OSHA Vacated PELs: Ampicillin: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by
OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or
European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Section 9 - Physical and Chemical Properties
Physical State: Solid
Appearance: white to off-white
Odor: none reported
pH: Not available.
Vapor Pressure: Not applicable.
Vapor Density: Not available.
Evaporation Rate:Not applicable.
Viscosity: Not applicable.
Boiling Point: Not available.
Freezing/Melting Point:202 deg C
Decomposition Temperature:Not available.
Solubility: Very soluble in water.
Specific Gravity/Density:Not available.
Molecular Formula:C16H19N3O4S
Molecular Weight:349.4

Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: High temperatures, incompatible materials, dust generation,
Incompatibilities with Other Materials: Strong oxidizers.
Hazardous Decomposition Products: Carbon monoxide, oxides of nitrogen, oxides of
sulfur, carbon dioxide.
Hazardous Polymerization: Has not been reported.

CAS# 69-53-4: XH8350000; XH8360000
CAS# 69-53-4:
Oral, mouse: LD50 = >5 gm/kg;
Oral, mouse: LD50 = 15.2 gm/kg;
Oral, rat: LD50 = 10 gm/kg;
CAS# 69-53-4: Not listed by ACGIH, IARC, NTP, or CA Prop 65.
Epidemiology: No information available.
Teratogenicity: No information found
Reproductive Effects: No information found
Mutagenicity: No information found
Neurotoxicity: No information found
Other Studies:

Ecotoxicity: No data available. No information available.
Environmental: No information reported.
Physical: No information available.
Other: None.

Chemical waste generators must determine whether a discarded chemical is classified as a
hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR
Parts 261.3. Additionally, waste generators must consult state and local hazardous waste
regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Canada TDG
Shipping Name:
Hazard Class:
UN Number:
Packing Group:


CAS# 69-53-4 is not listed on the TSCA inventory. It is for research and development
use only.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
Section 313 No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants.
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous Substances under the
None of the chemicals in this product are listed as Priority Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
None of the chemicals in this product are considered highly hazardous by OSHA.
CAS# 69-53-4 can be found on the following state right to know lists: New Jersey.
California Prop 65
California No Significant Risk Level: None of the chemicals in this product are listed.

European/International Regulations

European Labeling in Accordance with EC Directives
Hazard Symbols:
Risk Phrases:

R 36/37/38 Irritating to eyes, respiratory system and skin.
R 42/43 May cause sensitization by inhalation and skin contact.

Safety Phrases:

S 26 In case of contact with eyes, rinse immediately with plenty of
water and seek medical advice.
S 36/37/39 Wear suitable protective clothing, gloves and eye/face pr

WGK (Water Danger/Protection)

CAS# 69-53-4: No information available.
Canada - DSL/NDSL
CAS# 69-53-4 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of D2A, D2B.
This product has been classified in accordance with the hazard criteria of the Controlled
Products Regulations and the MSDS contains all of the information required by those
Canadian Ingredient Disclosure List

MSDS Creation Date: 11/17/2005
Revision #1 Date: 11/17/2005
The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.



Bibliografía sobre Tartamudez publicada en las principales revistas científicas de habla inglesa durante el año 2002 Adeyoju, AB, Olujohungbe, ABK, Morris, J, et al. (2002). Priapism in sickle-cell disease; incidence, risk factors and complications - an international multicentre study. BJU INT 90 (9): 898-902 DEC Ambrose, NG, Yairi, E (2002). The Tudor Study: Data and ethics.

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