Bringing farmers evidence based knowledge on improving your
Liver Fluke or Fasciolosis Winter issue 2012
worm cal ed “Fasciola hepatica”.
milk-, weight-,and fertility- decline.
which the mud snail is essential and choice for your cattle. Annual
Burrenvets Spanish Point 0657084019 Ennistymon 0657071155 http://www.animalhealthireland.ie Health Calendar October, November, December Flukicidal Products:
Only oral Triclabendazole products can be used at housing as these target early immature, older
immature and adult flukes. W hen dosing at housing with “older immature and adult flukicide”: after 6 weeks check dung samples
and/or retreat OR delay administration of this flukicide to 6-8 weeks after housing. W hen dosing with only adult flukicide: delay and after 2 months check dung samples and/or retreat.
Dry Cow Therapy: Prevention of Pneumonia in Weanlings choose well and do well
Weanling pneumonia is caused by different viruses; Bovine
Dry cow therapy (DCT) is the best chance of curing a
Herpesvirus1 (IBR), Bovine Respiratory Syncytial Virus (BRSV),
persistent mastitis infection (often Staph Aureus) and
Parainfluenza virus (PI3) and bacteria; Pasteurella,
can reduce new infections during dry period.
Mannheimia, Mycoplasma, Histophilus. But pneumonia is a
Unfortunately when done incorrectly it could caus
classic multi-factorial disease; only a combination of
infectious agents with inappropriate husbandry and management causes outbreaks. Therefor prevention
Choose well: al the cows should be treated: blanket
treatment. Selective treatment is only an option when
Lungworm control min 2 weeks prior to weaning.
al the cows SCC are individual y monitored (milk
Lungworm infection results in damaged lungs which are
recording and mastitis records) and herd average
more susceptible to bacteria and viruses.
<200000. The choice of antibiotic depends on the
Optimalise environment conditions: ideal y wean
bacteria prevalent on the farm. Take, if not done
previous, milksamples of cows with high SCC at
Weaning has shown to be stressful for more than 7 days,
minimum 3 weeks before drying off and we can sent
affecting adversely the immune system. Delay
these to the lab for culture and antibiotic sensitivity
additional stressors; dehorning, castration, diet change,
tests. Teat sealers can be used together with antibiotic
housing, re-grouping for 2-4 weeks post weaning.
DCT or alone in confirmed uninfected cows.
Introduce concentrates at least a month prior to
Do well: dry off abruptly, milk out as usual, wear clean
weaning, increase gradual y and intent calves to eat 1
gloves, disinfect teat ends, insert the nozzle partial y in
kg/day at weaning, continue after weaning.
the teat end, insert the content of the DCT and
Take up to 1/3 of cows, from the group, don’t move the
massage it up the teat into the udder and teat dip,
calves. Repeat at interval of min 5 days.
mark cow and record treatment: product, date, id cow
Do not sell until at least 2 weeks after weaning
and milk withdrawal period. Don’t al ow cows to lie for 2
Eradication of BVD improves calf’s immune system.
hours, than put cows in dry, clean paddock or cubicles.
Start vaccination against pneumonia at least 6 weeks
Winter 2012 ● Volume 1, Issue 4 ● Burrenvets ● (065) 7084019
Organism list not requested in this search BIOLOGICAL ACTIVITIES ISOLATED FOR XANTHOHUMOL% XANTHOHUMOL (FLAVONOID) PHARMACOLOGY OF COMPOUND - IN VITRO * IC50 31.4 MICROMOLS/ACTIVE * L10219 * VS.CDNA-EXPRESSED HUMAN CYP1A2. PHARMACOLOGY OF COMPOUND - IN VITRO * CONCENTRATION VARIABLE NOT STATED ACTIVE * SEE ARTICLE FOR OTHER TEST RESULTS. * L30201 *PHARMACOLOGY OF COMPOUND - IN VITRO * C