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Material Safety Data Sheet
Tetracycline HCl MSDS
Section 1: Chemical Product and Company Identification
14025 Smith Rd.
US Sales: 1-800-901-7247
International Sales: 1-281-441-4400
TSCA 8(b) inventory: Tetracycline HCl
CHEMTREC (24HR Emergency Telephone), call:
International CHEMTREC, call:
For non-emergency assistance, call:
Section 2: Composition and Information on Ingredients
% by Weight
Toxicological Data on Ingredients:
Tetracycline HCl: ORAL (LD50): Acute: 6443 mg/kg [Rat].
Section 3: Hazards Identification
Potential Acute Health Effects:
Hazardous in case of ingestion, of inhalation. Slightly hazardous in case of skin contact (irritant, permeator), of eye contact
Potential Chronic Health Effects:
Non-permeator by skin. CARCINOGENIC EFFECTS: Not available. MUTAGENIC EFFECTS: Not available. TERATOGENIC
EFFECTS: Not available. DEVELOPMENTAL TOXICITY: PROVEN The substance is toxic to the reproductive system, liver.
Repeated or prolonged exposure to the substance can produce target organs damage.
Section 4: First Aid Measures
No known effect on eye contact, rinse with water for a few minutes.
After contact with skin, wash immediately with plenty of water. Gently and thoroughly wash the contaminated skin with running
water and non-abrasive soap. Be particularly careful to clean folds, crevices, creases and groin. Cover the irritated skin with an
emollient. If irritation persists, seek medical attention. Wash contaminated clothing before reusing.
Serious Skin Contact:
Allow the victim to rest in a well ventilated area. Seek immediate medical attention.
Do not induce vomiting. Loosen tight clothing such as a collar, tie, belt or waistband. If the victim is not breathing, perform
mouth-to-mouth resuscitation. Seek immediate medical attention.
Section 5: Fire and Explosion Data
Flammability of the Product:
May be combustible at high temperature.
Products of Combustion:
These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2.).
Fire Hazards in Presence of Various Substances:
Explosion Hazards in Presence of Various Substances:
Risks of explosion of the product in presence of mechanical impact: Not available. Risks of explosion of the product in
presence of static discharge: Not available.
Fire Fighting Media and Instructions:
SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
Special Remarks on Fire Hazards:
Special Remarks on Explosion Hazards:
Section 6: Accidental Release Measures
Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on
the contaminated surface and dispose of according to local and regional authority requirements.
Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the
contaminated surface and allow to evacuate through the sanitary system.
Section 7: Handling and Storage
Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk, evaporate the residue under a
fume hood. Ground all equipment containing material. Do not ingest. Do not breathe dust. Wear suitable protective clothing In
case of insufficient ventilation, wear suitable respiratory equipment If ingested, seek medical advice immediately and show the
container or the label.
Keep container dry. Keep in a cool place. Ground all equipment containing material. Keep container tightly closed. Keep in acool, well-ventilated place. Combustible materials should be stored away from extreme heat and away from strong oxidizingagents.
Section 8: Exposure Controls/Personal Protection
Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended
exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants
below the exposure limit.
Safety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent.
Personal Protection in Case of a Large Spill:
Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoid
inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this
Section 9: Physical and Chemical Properties
Physical state and appearance:
Solid. (Powdered solid.)
pH (1% soln/water):
Water/Oil Dist. Coeff.:
Ionicity (in Water):
Section 10: Stability and Reactivity Data
The product is stable.
Conditions of Instability:
Incompatibility with various substances:
Non-corrosive in presence of glass.
Special Remarks on Reactivity:
Special Remarks on Corrosivity:
Section 11: Toxicological Information
Routes of Entry:
Toxicity to Animals:
Acute oral toxicity (LD50): 6443 mg/kg [Rat].
Chronic Effects on Humans:
DEVELOPMENTAL TOXICITY: PROVEN The substance is toxic to the reproductive system, liver.
Other Toxic Effects on Humans:
Hazardous in case of ingestion, of inhalation. Slightly hazardous in case of skin contact (irritant, permeator).
Special Remarks on Toxicity to Animals:
Special Remarks on Chronic Effects on Humans:
May affect teeth and bones.
Special Remarks on other Toxic Effects on Humans:
Section 12: Ecological Information
BOD5 and COD:
Products of Biodegradation:
Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise.
Toxicity of the Products of Biodegradation:
The products of degradation are more toxic.
Special Remarks on the Products of Biodegradation:
May decompose in the presence of light.
Section 13: Disposal Considerations
Section 14: Transport Information
Not a DOT controlled material (United States).
Special Provisions for Transport:
Section 15: Other Regulatory Information
Federal and State Regulations:
California prop. 65: This product contains the following ingredients for which the State of California has found to cause cancer,birth defects or other reproductive harm, which would require a warning under the statute: Tetracycline HCl California prop. 65:This product contains the following ingredients for which the State of California has found to cause birth defects which wouldrequire a warning under the statute: Tetracycline HCl TSCA 8(b) inventory: Tetracycline HCl
OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).
CLASS D-2A: Material causing other toxic effects (VERY TOXIC).
This product is not classified according to the EU regulations.
National Fire Protection Association (U.S.A.):
Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Wear appropriate respirator
when ventilation is inadequate. Safety glasses.
Section 16: Other Information
Other Special Considerations:
10/10/2005 12:01 AM
11/01/2010 12:00 PM
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ª 2011 Adis Data Information BV. All rights reserved. Role of Cannabinoids in Multiple SclerosisJohn P. Zajicek1 and Vicentiu I. Apostu21 Clinical Neurology Research Group, Peninsula College of Medicine and Dentistry, Plymouth, UK2 Clinical Neurology Research Group, Peninsula Medical School, Plymouth, UKAbstract . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .