Material Safety Data Sheet Tetracycline HCl MSDS Section 1: Chemical Product and Company Identification Product Name: Tetracycline HCl Contact Information: Catalog Codes: SLT3640, SLT1624 Sciencelab.com, Inc. 14025 Smith Rd. CAS#: 64-75-5 RTECS: QI9100000
US Sales: 1-800-901-7247 International Sales: 1-281-441-4400 TSCA: TSCA 8(b) inventory: Tetracycline HCl CI#: Not available. CHEMTREC (24HR Emergency Telephone), call: Synonym: 4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-
International CHEMTREC, call: 1-703-527-3887 Chemical Name: Not available. For non-emergency assistance, call: 1-281-441-4400 Chemical Formula: C22H24N2O8.HCl Section 2: Composition and Information on Ingredients Composition: % by Weight Toxicological Data on Ingredients: Tetracycline HCl: ORAL (LD50): Acute: 6443 mg/kg [Rat]. Section 3: Hazards Identification Potential Acute Health Effects: Hazardous in case of ingestion, of inhalation. Slightly hazardous in case of skin contact (irritant, permeator), of eye contact (irritant). Potential Chronic Health Effects: Non-permeator by skin. CARCINOGENIC EFFECTS: Not available. MUTAGENIC EFFECTS: Not available. TERATOGENIC EFFECTS: Not available. DEVELOPMENTAL TOXICITY: PROVEN The substance is toxic to the reproductive system, liver. Repeated or prolonged exposure to the substance can produce target organs damage. Section 4: First Aid Measures Eye Contact: No known effect on eye contact, rinse with water for a few minutes. Skin Contact: After contact with skin, wash immediately with plenty of water. Gently and thoroughly wash the contaminated skin with running water and non-abrasive soap. Be particularly careful to clean folds, crevices, creases and groin. Cover the irritated skin with an emollient. If irritation persists, seek medical attention. Wash contaminated clothing before reusing. Serious Skin Contact: Not available. Inhalation: Allow the victim to rest in a well ventilated area. Seek immediate medical attention. Serious Inhalation: Not available. Ingestion: Do not induce vomiting. Loosen tight clothing such as a collar, tie, belt or waistband. If the victim is not breathing, perform mouth-to-mouth resuscitation. Seek immediate medical attention. Serious Ingestion: Not available. Section 5: Fire and Explosion Data Flammability of the Product: May be combustible at high temperature. Auto-Ignition Temperature: Not available. Flash Points: Not available. Flammable Limits: Not available. Products of Combustion: These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2.). Fire Hazards in Presence of Various Substances: Not available. Explosion Hazards in Presence of Various Substances: Risks of explosion of the product in presence of mechanical impact: Not available. Risks of explosion of the product in presence of static discharge: Not available. Fire Fighting Media and Instructions: SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use water spray, fog or foam. Do not use water jet. Special Remarks on Fire Hazards: Not available. Special Remarks on Explosion Hazards: Not available. Section 6: Accidental Release Measures Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements. Large Spill: Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate through the sanitary system. Section 7: Handling and Storage Precautions: Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk, evaporate the residue under a fume hood. Ground all equipment containing material. Do not ingest. Do not breathe dust. Wear suitable protective clothing In case of insufficient ventilation, wear suitable respiratory equipment If ingested, seek medical advice immediately and show the container or the label. Storage:
Keep container dry. Keep in a cool place. Ground all equipment containing material. Keep container tightly closed. Keep in acool, well-ventilated place. Combustible materials should be stored away from extreme heat and away from strong oxidizingagents. Section 8: Exposure Controls/Personal Protection Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit. Personal Protection: Safety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves. Personal Protection in Case of a Large Spill: Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product. Exposure Limits: Not available. Section 9: Physical and Chemical Properties Physical state and appearance: Solid. (Powdered solid.) Odor: Odorless. Taste: Not available. Molecular Weight: 480.89 g/mole Color: Yellow. pH (1% soln/water): Not available. Boiling Point: Decomposes. Melting Point: 214°C (417.2°F) Critical Temperature: Not available. Specific Gravity: Not available. Vapor Pressure: Not applicable. Vapor Density: Not available. Volatility: Not available. Odor Threshold: Not available. Water/Oil Dist. Coeff.: Not available. Ionicity (in Water): Not available. Dispersion Properties: Not available. Solubility: Not available. Section 10: Stability and Reactivity Data Stability: The product is stable. Instability Temperature: Not available. Conditions of Instability: Not available. Incompatibility with various substances: Not available. Corrosivity: Non-corrosive in presence of glass. Special Remarks on Reactivity: Not available. Special Remarks on Corrosivity: Not available. Polymerization: No. Section 11: Toxicological Information Routes of Entry: Inhalation. Ingestion. Toxicity to Animals: Acute oral toxicity (LD50): 6443 mg/kg [Rat]. Chronic Effects on Humans: DEVELOPMENTAL TOXICITY: PROVEN The substance is toxic to the reproductive system, liver. Other Toxic Effects on Humans: Hazardous in case of ingestion, of inhalation. Slightly hazardous in case of skin contact (irritant, permeator). Special Remarks on Toxicity to Animals: Not available. Special Remarks on Chronic Effects on Humans: May affect teeth and bones. Special Remarks on other Toxic Effects on Humans: Not available. Section 12: Ecological Information Ecotoxicity: Not available. BOD5 and COD: Not available. Products of Biodegradation: Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise. Toxicity of the Products of Biodegradation: The products of degradation are more toxic. Special Remarks on the Products of Biodegradation: May decompose in the presence of light. Section 13: Disposal Considerations Waste Disposal: Section 14: Transport Information DOT Classification: Not a DOT controlled material (United States). Identification: Not applicable. Special Provisions for Transport: Not applicable. Section 15: Other Regulatory Information Federal and State Regulations:
California prop. 65: This product contains the following ingredients for which the State of California has found to cause cancer,birth defects or other reproductive harm, which would require a warning under the statute: Tetracycline HCl California prop. 65:This product contains the following ingredients for which the State of California has found to cause birth defects which wouldrequire a warning under the statute: Tetracycline HCl TSCA 8(b) inventory: Tetracycline HCl
Other Regulations: OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200). Other Classifications: WHMIS (Canada): CLASS D-2A: Material causing other toxic effects (VERY TOXIC). DSCL (EEC): This product is not classified according to the EU regulations. HMIS (U.S.A.): Health Hazard: 1 Fire Hazard: 1 Reactivity: 0 Personal Protection: E National Fire Protection Association (U.S.A.): Health: 1 Flammability: 1 Reactivity: 0 Specific hazard: Protective Equipment: Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Wear appropriate respirator when ventilation is inadequate. Safety glasses. Section 16: Other Information References: Not available. Other Special Considerations: Not available. Created: 10/10/2005 12:01 AM Last Updated: 11/01/2010 12:00 PM The information above is believed to be accurate and represents the best information currently available to us. However, wemake no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assumeno liability resulting from its use. Users should make their own investigations to determine the suitability of the information fortheir particular purposes. In no event shall ScienceLab.com be liable for any claims, losses, or damages of any third party or forlost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if ScienceLab.comhas been advised of the possibility of such damages.
CF II: How to prepare a prefect CPC – EBM exercise 1. Do you have a case scenario for your CPC? If yes, please write a summary of your patient scenario in the box below. If no, please click here to select one of the five case scenarios and copy and paste it to the box below: Ms EH, a 23 yo Hispanic female presents to the GI clinic complaining of episodes of right sided abdominal
ª 2011 Adis Data Information BV. All rights reserved. Role of Cannabinoids in Multiple SclerosisJohn P. Zajicek1 and Vicentiu I. Apostu21 Clinical Neurology Research Group, Peninsula College of Medicine and Dentistry, Plymouth, UK2 Clinical Neurology Research Group, Peninsula Medical School, Plymouth, UKAbstract . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .